218168-25-3

Upstream product

• 218168-22-0 methyl (-)-(S)-3,5-dioxo-6-(p-tolylsulfinyl)hexanoate 
• 218168-23-1 (5R,SS)-methyl 5-hydroxy-3-oxo-6-(p-tolylsulfinyl)hexanoate 

Downstream Products

• 218168-35-5 [(4R,6R)-2,2-Dimethyl-6-((S)-toluene-4-sulfinylmethyl)-[1,3]dioxan-4-yl]-acetic acid methyl ester 
• 799247-43-1 (3R,5R,SS)-N-methoxy-N-methyl-3,5-dihydroxy-6-(p-tolylsulfinyl)hexanamide 
• 799247-47-5 (2R,4R,6R,SS)-2,4-dimethoxy-2-methyl-6-[(p-tolylsulfinyl)methyl]-tetrahydro-2H-pyran 
• 799247-46-4 (2R,4R,6R,SS)-2-methoxy-2-methyl-6-[(p-tolylsulfinyl)methyl]-tetrahydro-2H-pyran-4-ol 
• 799247-45-3 (4R,6R,SS)-4,6-isopropylidenedioxy-7-(p-tolylsulfinyl)heptan-2-one 
• 799247-44-2 (3R,5R,SS)-N-methoxy-N-methyl-3,5-isopropylidenedioxy-6-(p-tolylsulfinyl)hexanamide 

Relevant academic research and scientific papers

Asymmetric synthesis of the tetrahydropyran ring, C32-C38 fragment, of phorboxazoles

(Chemical Equation Presented) The asymmetric synthesis of a model aldehyde (2R,6R)-2 and the C32-C38 fragment of phorboxazoles, (2R,4R,6R)-1, is described using a sulfoxide as chiral auxiliary. Key advances include the stereoselective reductions of β-keto

Enantioselective synthesis of C2-symmetric hexols from β-δ- diketosulfoxides

An enantioselective synthesis of (1,2S,4S,8S,10S,11)- hexahydroxyundecane, a C2-symmetric hexol precursor of the alkaloid (-)- lythranidine, is described. This convergent synthesis was based on the stereoselective reduction of two different β-δ