218281-35-7

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 218281-33-5 3(S)-azide-4(S)-fluoromethyl-1-[N-1(R)-phenylethyl]-2-pyrrolidone 
• 190957-22-3 (4R,1'R)-1-(1'-phenylethyl)-4-hydroxymethylpyrrolidin-2-one 
• 252051-14-2 (4R,1'R)-1-(1'-phenylethyl)-4-methanesulfonyloxymethylpyrrolidin-2-one 
• 218281-29-9 4(S)-fluoromethyl-1-[N-1(R)-phenylethyl]-2-pyrrolidone 
• 218281-31-3 4(S)-fluoromethyl-3(R)-hydroxy-1-[N-1(R)-phenylethyl]-2-pyrrolidone 
• 1027014-09-0 Methanesulfonic acid (3R,4S)-4-fluoromethyl-2-oxo-1-((R)-1-phenyl-ethyl)-pyrrolidin-3-yl ester 

Downstream Products

• 218281-25-5 7-[3(S)-amino-4(S)-fluoromethyl-1-pyrrolidinyl]-6-fluoro-1-cyclopropyl-1,4-dihydro-8-methoxy-4-oxoquinoline-3-carboxylic acid 
• 218281-40-4 3(S)-tert-butoxycarbonylamino-4(S)-fluoromethylpyrrolidine 

Relevant academic research and scientific papers

Studies on 8-methoxyquinolones: Synthesis and antibacterial activity of 7-(3-amino-4-substituted)pyrrolidinyl derivatives

A series of 8-methoxyquinolones bearing 3-amino-4-methylpyrrolidines or 3-amino-4-fluoromethylpyrrolidines at the C-7 position was synthesized and their physicochemical and biological properties were evaluated. All of the compounds synthesized showed more