218281-25-5

Usage

Uses

Used in Pharmaceutical Industry:
(3S,4S)-7-[3-Amino-4-(fluoromethyl)pyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid is used as a novel antibiotic agent for its demonstrated antibacterial activity against a range of pathogens. Its potential to inhibit the bacterial DNA gyrase enzyme makes it a candidate for further research and development in combating antibiotic-resistant bacteria.
The precise mode of action and spectrum of activity of (3S,4S)-7-[3-Amino-4-(fluoromethyl)pyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid are still under investigation, which indicates that ongoing research is necessary to fully understand and harness its potential as an antibiotic. This could lead to the development of new treatments for bacterial infections that are resistant to existing antibiotics, addressing a significant global health concern.

Upstream product

• 218281-45-9 7-((3S,4S)-3-tert-Butoxycarbonylamino-4-fluoromethyl-pyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid 
• 218281-29-9 4(S)-fluoromethyl-1-[N-1(R)-phenylethyl]-2-pyrrolidone 
• 1033718-06-7 3-(S)-tert-butoxycarbonylamino-4-(S)-fluoromethylpyrrolidine 
• 112811-72-0 1-cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid 
• 218281-35-7 3(S)-tert-butoxycarbonylamino-4(S)-fluoromethyl-1-[N-1(R)-phenylethyl]-2-pyrrolidone 
• 218281-37-9 3(S)-tert-butoxycarbonylamino-4(S)-fluoromethyl-1-[N-1(R)-phenylethyl]pyrrolidine 
• 1027014-09-0 Methanesulfonic acid (3R,4S)-4-fluoromethyl-2-oxo-1-((R)-1-phenyl-ethyl)-pyrrolidin-3-yl ester 
• 218281-33-5 3(S)-azide-4(S)-fluoromethyl-1-[N-1(R)-phenylethyl]-2-pyrrolidone 
• 218281-40-4 3(S)-tert-butoxycarbonylamino-4(S)-fluoromethylpyrrolidine 
• 218281-31-3 4(S)-fluoromethyl-3(R)-hydroxy-1-[N-1(R)-phenylethyl]-2-pyrrolidone 
• 252051-14-2 (4R,1'R)-1-(1'-phenylethyl)-4-methanesulfonyloxymethylpyrrolidin-2-one 
• 190957-22-3 (4R,1'R)-1-(1'-phenylethyl)-4-hydroxymethylpyrrolidin-2-one 

Relevant academic research and scientific papers

CIS-SUBSTITUTED FLUOROMETHYLPYRROLIDINE DERIVATIVE

An antibacterial drug having potent antibacterial activities upon various bacteria including resistant strains and high safety is disclosed, which comprises as an active ingredient, quinolone derivatives represented by the following formula (I), its salts

Studies on 8-methoxyquinolones: Synthesis and antibacterial activity of 7-(3-amino-4-substituted)pyrrolidinyl derivatives

A series of 8-methoxyquinolones bearing 3-amino-4-methylpyrrolidines or 3-amino-4-fluoromethylpyrrolidines at the C-7 position was synthesized and their physicochemical and biological properties were evaluated. All of the compounds synthesized showed more