2189-52-8 Usage
Uses
Used in Pharmaceutical Industry:
(1R,5S)-3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yloxy)-8-azabicyclo[3.2.1]octane (2Z)-but-2-enedioate is used as a pharmaceutical candidate for [application reason] due to its unique chemical structure and potential biological activity.
Used in Chemical Research:
In the field of chemical research, (1R,5S)-3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yloxy)-8-azabicyclo[3.2.1]octane (2Z)-but-2-enedioate serves as a subject of study for understanding its properties, reactivity, and potential applications in various chemical processes.
Used in Material Science:
(1R,5S)-3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yloxy)-8-azabicyclo[3.2.1]octane (2Z)-but-2-enedioate is utilized in material science for the development of new materials with specific properties, such as improved stability, reactivity, or selectivity, based on its unique chemical structure.
Check Digit Verification of cas no
The CAS Registry Mumber 2189-52-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,1,8 and 9 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 2189-52:
(6*2)+(5*1)+(4*8)+(3*9)+(2*5)+(1*2)=88
88 % 10 = 8
So 2189-52-8 is a valid CAS Registry Number.
2189-52-8Relevant academic research and scientific papers
Structure-based design, synthesis and structure-activity relationships of dibenzosuberyl- and benzoate-substituted tropines as ligands for acetylcholine-binding protein
Edink, Ewald,Akdemir, Atilla,Jansen, Chimed,Elk, René Van,Zuiderveld, Obbe,De Kanter, Frans J.J.,Van Muijlwijk-Koezen, Jacqueline E.,Smit, August B.,Leurs, Rob,De Esch, Iwan J.P.
, p. 1448 - 1454 (2012/04/04)
Using structure-based optimization procedures on in silico hits, dibenzosuberyl- and benzoate substituted tropines were designed as ligands for acetylcholine-binding protein (AChBP). This protein is a homolog to the ligand binding domain of the nicotinic acetylcholine receptor (nAChR). Distinct SAR is observed between two AChBP species variants and between the α7 and α4β2 nAChR subtype. The AChBP species differences are indicative of a difference in accessibility of a ligand-inducible subpocket. Hereby, we have identified a region that can be scrutinized to achieve selectivity for nicotinic receptor subtypes.
