21898-43-1

Basic information

• Product Name: (1-methyl-1H-pyrrol-2-yl)(oxo)acetic acid
• Synonyms: (1-methyl-1H-pyrrol-2-yl)(oxo)acetic acid;1H-pyrrole-2-acetic acid, 1-methyl-alpha-oxo-;(1-methyl-1H-pyrrol-2-yl)(oxo)acetic acid(SALTDATA: FREE);2-(1-methyl-2-pyrrolyl)-2-oxoacetic acid;2-(1-methylpyrrol-2-yl)-2-oxoacetic acid;2-(1-methylpyrrol-2-yl)-2-oxo-acetic acid;2-(1-methylpyrrol-2-yl)-2-oxo-ethanoic acid;2-keto-2-(1-methylpyrrol-2-yl)acetic acid
• CAS NO: 21898-43-1
• Molecular Formula: C₇H₇NO₃
• Molecular Weight: 153.13538
• Mol File: 21898-43-1.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (1-methyl-1H-pyrrol-2-yl)(oxo)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (1-methyl-1H-pyrrol-2-yl)(oxo)acetic acid(21898-43-1)
• EPA Substance Registry System: (1-methyl-1H-pyrrol-2-yl)(oxo)acetic acid(21898-43-1)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 21898-43-1(Hazardous Substances Data)

Usage

General Description

(1-methyl-1H-pyrrol-2-yl)(oxo)acetic acid is a chemical compound with the molecular formula C7H7NO3. Its structure consists of a pyrrole ring with a methyl group and a carboxylic acid group attached. The compound is a heterocyclic aromatic carboxylic acid and is a derivative of pyrrole. It is commonly used as a building block in organic synthesis and pharmaceutical research. The compound may have potential applications in the development of new drugs and materials due to its unique structure and properties.

Upstream product

• 932-16-1 N-methyl-2-acetylpyrrole 
• 96-54-8 N-Methylpyrrole 
• 79-37-8 oxalyl dichloride 

Downstream Products

• 21898-59-9 1-methylpyrrole-2-acetic acid 
• 51856-79-2 N-methyl-2-(methoxycarbonylmethyl)pyrrole 
• 33369-52-7 methyl 1-Methyl-5-(4-methylbenzoyl)-1H-pyrrole-2-acetate 
• 26171-23-3 1-methyl-5-(p-toluoyl)pyrrole-2-acetic acid 
• 80096-44-2 (5-benzoyl-1-methyl-1H-pyrrol-2-yl)acetic acid methyl ester 
• 26280-19-3 5-benzoyl-1-methyl-pyrrole-2-acetic acid 

Relevant articles and documents

Synthesis, antimicrobial, and anti-inflammatory activities of acetamido pyrrolyl azoles

The acetamido pyrrolyl oxazoles/thiazoles/imidazoles were prepared and tested for their antimicrobial and anti-inflammatory activities. The nitro substituted acetamido pyrrolyl thiazole (11f) and pyrrolyl imidazole (12f) exhibited promising antibacterial activity against K. pneumoniae. The compound 12f showed good antifungal activity against P. chrysogenum. The methoxy acetamido pyrrolyl oxazole (10c) displayed potential anti-inflammatory activity.

Synthesis and process optimization of amtolmetin: An antiinflammatory agent

Efforts toward the synthesis and process optimization of amtolmetin guacil 1 are described. High-yielding electrophilic substitution followed by Wolf-Kishner reduction are the key features in the novel synthesis of tolmetin 2 which is an advanced intermediate of 1.