21908-07-6

Basic information

• Product Name: 2-formyl-3-pyridinecarboxylic acid ethyl ester
• Synonyms: 2-formyl-3-pyridinecarboxylic acid ethyl ester;Ethyl 2-formylnicotinate;2-Formyl-nicotinic acid ethyl ester
• CAS NO: 21908-07-6
• Molecular Formula: C₉H₉NO₃
• Molecular Weight: 179.17266
• Mol File: 21908-07-6.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-formyl-3-pyridinecarboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-formyl-3-pyridinecarboxylic acid ethyl ester(21908-07-6)
• EPA Substance Registry System: 2-formyl-3-pyridinecarboxylic acid ethyl ester(21908-07-6)

Safety Data

• Hazardous Substances Data: 21908-07-6(Hazardous Substances Data)

Upstream product

• 75-09-2 dichloromethane 
• 2050-22-8 2,3-diethyl pyridinedicarboxylate 
• 1721-26-2 ethyl 2-methyl nicotinate 
• 62759-80-2 3-amino-4,4-diethoxycrotonic acid ethyl ester 
• 23504-40-7 Ethyl 2-diethoxymethylnicotinate 

Downstream Products

• 137282-14-5 (2S)-4-methyl-2-<<(2S)-2-(5-oxo-5,7-dihydropyrrolo<3,4-b>pyridin-6-yl)-3-phenylpropionyl>amino>pentanoic acid methyl ester 
• 137281-93-7 (3S)-4-cyclohexyl-2-hydroxy-3-<<(2S)-4-methyl-2-<<(2S)-2-(5-oxo-5,7-dihydropyrrolo<3,4-b>pyridin-6-yl)-3-phenylpropionyl>amino>pentanoyl>amino>butyric acid methyl ester 
• 137282-15-6 (2S)-4-methyl-2-<<(2S)-2-(5-oxo-5,7-dihydropyrrolo<3,4-b>pyridin-6-yl)-3-phenylpropionyl>amino>pentanoic acid 
• 5657-51-2 7H-furo[3,4-b]pyridin-5-one 

Relevant articles and documents

Heterocyclic compounds as ligands of the GABAA receptor

Disclosed are heterocyclic compounds of the formula and the pharmaceutically acceptable salts thereof wherein the variables A, V, Y, J, E, X, T, G, Q, W, Z, b, n and m are defined herein. These compounds are highly selective agonists, antagonists or inverse agonists for GABAA brain receptors or prodrugs of agonists, antagonists or inverse agonists for GABAA brain receptor.

Synthesis of 6-Phenyl Substituted 2-Formylnicotinates

A verastile synthesis of 2-formylnicotinates 6 (R' = Me) and 7 (R' = Et) is described. 6-Phenyl substituted 2-diethoxymethylnicotinates 14/15 are prepared first starting by cyclocondensation of 3-amino-4,4-diethoxybut-2-enoates 12/13 with Mannich base hydrochlorides 1 or β-aminovinyl ketones 16. Subsequent hydrolysis of the acetal function in 14/15 gives rise to the title compounds.

Heterocyclic hydrazines and hydrazones

N-carbamoyl-2-carboxyaryl-heterocyclic and hydrazinecarboximidamide-hydrazone derivatives, intermediates and processes for their preparation, agricultural compositions containing them and their use as agricultural chemicals, in particular herbicides.