21911-84-2

Basic information

• Product Name: 3-PHENYLAMINO-PROPIONIC ACID METHYL ESTER
• Synonyms: METHYL 3-(PHENYLAMINO)PROPANOATE;3-PHENYLAMINO-PROPIONIC ACID METHYL ESTER;methyl N-phenyl-beta-alaninate;methyl 3-anilinopropanoate;3-Anilinopropanoic acid methyl ester;3-Anilinopropionic acid methyl ester;N-Phenyl-β-alanine methyl ester;3-(phenylamino)propanoic acid methyl ester
• CAS NO: 21911-84-2
• Molecular Formula: C₁₀H₁₃NO₂
• Molecular Weight: 179.22
• EINECS: 244-656-8
• Mol File: 21911-84-2.mol
• Article Data: 61

Chemical Properties

• Boiling Point: 308.334 °C at 760 mmHg
• Flash Point: 140.276 °C
• Appearance: /
• Density: 1.107 g/cm³
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 3-PHENYLAMINO-PROPIONIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 3-PHENYLAMINO-PROPIONIC ACID METHYL ESTER(21911-84-2)
• EPA Substance Registry System: 3-PHENYLAMINO-PROPIONIC ACID METHYL ESTER(21911-84-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 21911-84-2(Hazardous Substances Data)

Usage

General Description

3-Phenylamino-propionic acid methyl ester is a chemical compound with the molecular formula C11H15NO2. It is a methyl ester derivative of 3-phenylamino-propionic acid, which is used in the synthesis of pharmaceuticals and other organic compounds. 3-PHENYLAMINO-PROPIONIC ACID METHYL ESTER is an organic compound that consists of a phenyl group attached to an amino-propionic acid molecule and a methyl ester group. It is commonly used as an intermediate in the production of various pharmaceuticals and organic compounds. This chemical is often used in the research and development of new drugs and can be found in various laboratory settings.

Upstream product

• 98-95-3 nitrobenzene 
• 292638-85-8 acrylic acid methyl ester 
• 21017-47-0 3-(phenylamino)propanamide 
• 1950-44-3 N,N-dimethyl-3-phenylaminopropionamide 
• 591-50-4 iodobenzene 
• 4138-35-6 methyl 3-aminopropanoate 
• 62-53-3 aniline 
• 3395-91-3 Methyl 3-bromopropionate 

Downstream Products

• 27139-02-2 N-(4-nitroso-phenyl)-β-alanine methyl ester 
• 99855-42-2 acide (N-phenyl acetamido)-3 propanoique 
• 616-45-5 2-pyrrolidinon 
• 13532-18-8 methyl 3-(methylthio)propionate 
• 872-54-8 Methyl-pyrrolidin-(2E)-ylidene-amine 
• 70961-62-5 N-methyl 3-methylthiopropionamide 
• 1199-80-0 2-(phenylimino)pyrrolidine 
• 4916-20-5 3-anilinopropionic acid hydrazide 
• 1001346-30-0 methyl 3-[(2-chloro-5-nitro-pyrimidin-4-yl)-phenyl-amino]propanoate 
• 1240530-77-1 methyl 3-((tert-butoxycarbonyl)(phenyl)amino)propanoate 
• 212322-35-5 1-Methyl-2-[N-(4-thiocarbamoyl-phenyl)aminomethyl]-indol-5-yl-carboxylic acid-N-phenyl-N-(2-methoxycarbonylethyl)-amide 
• 212322-34-4 2-[N-(4-cyanophenyl)aminomethyl]-indol-5-yl-carboxylic acid-N-phenyl-N-(2-methoxycarbonylethyl)-amide 
• 212322-33-3 1-tert-Butoxycarbonyl-2-methyl-indol-5-yl-carboxylic acid-N-phenyl-N-(2-methoxycarbonylethyl)-amide 

Relevant articles and documents

Aminomercuration-Demercuration of α,β-Unsaturated Esters; Synthesis of N-Aryl-β-aminocarboxylic Esters

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NOVEL HISTONE METHYLTRANSFERASE INHIBITORS

The present invention relates to novel compounds of formula (I) as defined herein. The compounds are inhibitors of histone methyltransferases of the seven-beta-strand family, in particular of KMT9.

Deep compositional understanding of TBA: AlCl3 ionic liquid for its applications

Chloroaluminate ionic liquids (ILs) have been immensely used as homogeneous catalyst in Friedel-Crafts reaction. We have recently synthesized chloroaluminate ILs by reacting aluminium chloride with a hydrophobic neutral ligand i.e. tributylamine (TBA:AlCl3). The current study elaborates on the investigations of the composition of the ionic liquids at various stages of their formation. The ionic liquids were synthesized using various mole ratios of tributyl amine and aluminium chloride in range of 1:1 to 1:2.3, in presence of an aromatic solvent in a one pot reaction. Various characterization techniques like Mass spectrometry, 27Al Nuclear Magnetic Resonance, 31P Nuclear Magnetic Resonance and Fourier Transform Infrared spectroscopy were used to elucidate the formation of various moieties of the TBA:AlCl3 Ionic Liquid. This study also elaborates on the investigations of the cationic and anionic moieties and their structure-property relationship for various applications. Various Friedel-Crafts reaction of industrial importance were performed using the ionic liquid having (Al2Cl7)?moiety to assess its performance and compared with conventional processes. The synthesized products were characterised by sophisticated analytical techniques like 1H NMR, 13C NMR, FTIR, GC–MS, GC-FID, to name a few. This class of ionic liquids also have importance in various electrochemical applications like aluminium deposition and aluminium batteries.