21915-56-0Relevant academic research and scientific papers
Synthesis, structural characterization and catalytic activity of a multifunctional enzyme mimetic oxoperoxovanadium(v) complex
Si, Tapan K.,Paul, Shiv S.,Drew, Michael G. B.,Mukherjea, Kalyan K.
scheme or table, p. 5805 - 5815 (2012/06/15)
The synthesis and structural characterization of a novel oxoperoxovanadium(v) complex [VO(O2)(PAH)(phen)] containing the ligands 2-phenylacetohydroxamic acid (PAHH) and 1,10-phenanthroline (phen) has been accomplished. The oxoperoxovanadium(v) complex was found to mimic both vanadate-dependent haloperoxidase (VHPO) activity as well as nuclease activity through effective interaction with DNA. The complex is the first example of a structurally characterized stable oxoperoxovanadium(v) complex with a coordinated bi-dentate hydroximate moiety (-CONHO-) from 2-phenylacetohydroximate (PAH). The oxoperoxovanadium(v) complex has been used as catalyst for the peroxidative bromination reaction of some unsaturated alcohols (e.g. 4-pentene-1-ol, 1-octene-3-ol and 9-decene-1-ol) in the presence of H2O2 and KBr. The catalytic products have been characterized by GC-MS analysis and spectrophotometric methods. The DNA binding of this complex has been established with CT DNA whereas the DNA cleavage was demonstrated with plasmid DNA. The interactions of the complex with DNA have been monitored by electronic absorption and fluorescence emission spectroscopy. Viscometric measurements suggest that the compound is a DNA intercalator. The nuclease activity of this complex was confirmed by gel electrophoresis studies.
Properties of Ti-beta zeolites synthesized by dry-gel conversion and hydrothermal methods
Tatsumi, Takashi,Jappar, Nizamidin
, p. 7126 - 7131 (2007/10/03)
The large-pore beta zeolite containing Ti has been synthesized in the presence of alkali cations (Na+) by a dry-gel conversion (DGC) technique using tetraethylammonium hydroxide (TEAOH) as a structure-directing agent. The obtained Ti-beta zeolites were compared with hydrothermally synthesized (HTS) Ti-beta. It was found that Ti-beta-DGC samples adsorbed less water (12-13 wt %) than Ti-beta-HTS (19 wt %), indicating that Ti-beta-DGC is more hydrophobic than Ti-beta-HTS. We propose that this leads to a higher activity for the former in the oxidation of cyclohexane. Upon being washed with H2SO4, the turnover number (TON) of DGC samples slightly increased for the oxidation of cyclohexane. DGC and HTS samples demonstrated no significant difference in the activity for oxidation reactions of unsaturated alcohols and C6-C8 cyclic alcohols.
TRANSFORMATION OF ALLYLIC EPOXIDES TO TETRAHYDROFURFURYL ALCOHOLS VIA HYDROBORATION
Zaidlewicz, Marek,Sarnowski, Ryszard
, p. 281 - 284 (2007/10/02)
The allylic epoxides (1)-(4) were transformed to the tetrahydrofurfuryl alcohols (17)-(20), respectively.The formation of (6) and (10) in the hydroboration-oxidation of (4) is interpreted.The monohydroboration-oxidation of (13) and (14) gave (15) and (16), respectively.
