Oxirane, 3-hydroxypropyl-

Base Information

• Chemical Name: Oxirane, 3-hydroxypropyl-
• CAS No.: 21915-56-0
• Molecular Formula: C5H10 O2
• Molecular Weight: 102.133
• Hs Code.: 2910900090
• Mol file: 21915-56-0.mol

Synonyms:1-Pentanol,4,5-epoxy- (8CI); Oxiranepropanol (9CI); 4,5-Epoxy-1-pentanol

Chemical Property of Oxirane, 3-hydroxypropyl-

Chemical Property:

• Boiling Point: 199.1±8.0 °C(Predicted)
• PKA: 15.11±0.10(Predicted)
• PSA: 32.76000
• Density: 1.065±0.06 g/cm3(Predicted)
• LogP: 0.15770

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Oxirane, 3-hydroxypropyl-

There total 3 articles about Oxirane, 3-hydroxypropyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 5.0%

n-Pent-4-enyl alcohol (821-09-0) → tetrahydrofurfuryl bromide (1192-30-9) + 3-bromotetrahydro-2H-pyran (13047-01-3) + 5-hydroxy-1,2-epoxypentane (21915-56-0)

Guidance literature:

With [VO(O)2(PAH)(Phen)]; dihydrogen peroxide; nitric acid; potassium bromide; In N,N-dimethyl-formamide; acetonitrile; at 20 ℃; for 5h;

DOI:10.1039/c2dt12505f

Reference yield:

1,2-epoxy-3-vinylpropane (6790-38-1) → Oxan-3-ol (19752-84-2) + Tetrahydrofurfuryl alcohol (97-99-4) + 5-hydroxy-1,2-epoxypentane (21915-56-0)

Guidance literature:

With sodium hydroxide; borane; dihydrogen peroxide; Yield given. Multistep reaction. Yields of byproduct given; 1.) THF, 0 deg C, 2 h, 2.) THF, 20 deg C, 2 h;

Reference yield:

n-Pent-4-enyl alcohol (821-09-0) → 4,5-epoxypentanal (65842-25-3) + 4-pentenal (2100-17-6) + 5-hydroxy-1,2-epoxypentane (21915-56-0)

Guidance literature:

With dihydrogen peroxide; hydrothermally synthesized Ti-Beta zeolite; In water; acetonitrile; at 49.85 ℃; for 3h;

DOI:10.1021/jp9816216

upstream raw materials:

1,2-epoxy-3-vinylpropane

n-Pent-4-enyl alcohol

Downstream raw materials:

(S)-tetrahydro-2H-pyran-3-ol

3-(R)-hydroxytetrahydropyran

Tetrahydrofurfuryl alcohol