21919-63-1Relevant academic research and scientific papers
3-acetoxy-6-hydroxy-2,4-dimethoxyacetophenone
Mukherjee, Shubhasish,Parmar, Virinder S.,Errington, William
, p. 123 - 125 (1998)
The title compound, C12H14O6, has been isolated from a Fries reaction on 3,6-dihydroxy-2,4-dimethoxyacetophenone. Its molecular structure contains an intramolecular hydrogen-bonded unit involving the -COCH3 and -OH substituents. The best plane through the acetoxy group makes a dihedral angle of 88.74 (5)° with the plane of the aromatic ring.
A practical and economical high-yielding, six-step sequence synthesis of a flavone: Application to the multigram-scale synthesis of ladanein
Martin-Benlloch, Xavier,Elhabiri, Mourad,Lanfranchi, Don Antoine,Davioud-Charvet, Elisabeth
, p. 613 - 617 (2014/06/09)
Herein we report a short and economic synthesis of the antiviral flavonoid lead ladanein (1). Ladanein is obtained from 2,6-dimethoxyquinone (11) in six steps with 51% overall yield. After a high-yielding reductive acetylation and Fries rearrangement, the
