219307-07-0

Usage

Formation

It is derived from the reaction of octanoic acid with phenol, resulting in the formation of an ester.

Usage as flavoring and fragrance agent

Due to its pleasant aroma and taste, 2-(4-octanoylphenyl)ethanol is commonly used in the flavoring and fragrance industry.

Application in cosmetics and personal care products

This chemical is utilized in various cosmetic and personal care products such as perfumes, lotions, and soaps.

Potential antioxidant and anti-inflammatory properties

Octanoylphenyl ethanol has been researched for its potential antioxidant and anti-inflammatory properties, making it a subject of interest in the pharmaceutical and medical industries.

Fields of application

2-(4-octanoylphenyl)ethanol possesses a range of applications in the fields of food, cosmetics, and health.

Upstream product

• 103-45-7 acetic acid phenethyl ester 
• 111-64-8 n-octanoic acid chloride 
• 162358-03-4 2-(4-octanoylphenyl)ethyl acetate 

Downstream Products

• 219307-01-4 4'-(2-iodoethyl)octanophenone 
• 162359-55-9 fingolimod 
• 162358-05-6 2-(4-Octylphenyl)ethyl alcohol 
• 162358-08-9 diethyl 2-acetamido-2-[2-(4-octylphenyl)ethyl]malonate 
• 162358-06-7 4-octylphenethyl methanesulfonate 
• 162358-07-8 2-(4-octylphenyl)-1-iodoethane 
• 162358-09-0 2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate 
• 162358-03-4 2-(4-octanoylphenyl)ethyl acetate 
• 162358-04-5 acetic acid 2-(4-octylphenyl)ethyl ester 

Relevant academic research and scientific papers

PROCESS FOR PREPARATION OF FINGOLIMOD

The present invention provides a process for preparation of fingolimod, a compound of Formula I or a pharmaceutically acceptable salt thereof, free of regioisomeric impurity compound of Formula IA

Synthesis of the key intermediate, diethyl 2-acetylamino-2-(2-(4- octanoylphenyl)ethyl)propane-1,3-dioate, of the immunomodulatory agent FTY720 (fingolimod)

The key intermediate, diethyl 2-acetylamino-2-(2-(4-octanoylphenyl)ethyl) propane-1,3-dioate (13), for the immunomodulatory agent FTY720 (2: fingolimod) was synthesized via Michael addition of diethyl(acetylamino) malonate (6) to 4-octanoylstyrene (12).

PROCESS FOR PREPARING 2-AMINO MALONIC ACID DERIVATIVES AND 2-AMINO-1,3 - PROPANEDIOL DERIVATIVES, AND INTERMEDIATES FOR PREPARING THE SAME

A process for preparing 2-amino malonic acid derivatives of formula (1): wherein A is linear or branched chain alkylene having from 1 to 10 carbon atoms, R1 is linear or branched chain alkyl having from 2 to 20 carbon atoms, R2 and R3 are the same or different, and are lower alkyl or aralkyl, and R4 is a protecting group, which process comprises the steps of reducing a compound of formula (6): wherein A is linear or branched chain alkylene having from 1 to 10 carbon atoms, R1 is linear or branched chain alkyl having from 2 to 20 carbon atoms, R2 and R3 are the same or different, and are lower alkyl or aralkyl, and R4 is a protecting group.