162358-06-7

Basic information

• Product Name: 4-Octylphenethyl methanesulfonate
• Synonyms: 4-Octylphenethyl methanesulfonate;2-(4-Octylphenyl)ethyl 1-Methanesulfonate;4-Octylphenethyl methanesulfote
• CAS NO: 162358-06-7
• Molecular Formula: C₁₇H₂₈O₃S
• Molecular Weight: 312.46742
• EINECS: -0
• Mol File: 162358-06-7.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 454.8±24.0 °C(Predicted)
• Appearance: /
• Density: 1.048±0.06 g/cm3 (20 ºC 760 Torr)
• Storage Temp.: Refrigerator
• Solubility: Chloroform, Ethyl Acetate
• CAS DataBase Reference: 4-Octylphenethyl methanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Octylphenethyl methanesulfonate(162358-06-7)
• EPA Substance Registry System: 4-Octylphenethyl methanesulfonate(162358-06-7)

Safety Data

• Hazardous Substances Data: 162358-06-7(Hazardous Substances Data)

Usage

Description

4-Octylphenethyl methanesulfonate is an organic compound that serves as an intermediate in the synthesis of various pharmaceutical compounds. It is an orange solid with unique chemical properties that make it valuable in the development of drugs and other applications.

Uses

Used in Pharmaceutical Industry:
4-Octylphenethyl methanesulfonate is used as an intermediate in the preparation of FTY720-d4 (F805002), a labelled derivative of ISP-1 (myriocin). ISP-1 is a fungal metabolite derived from the Chinese herb Iscaria sinclarii and is also a structural analogue of Sphingosine. This intermediate plays a crucial role in the development of drugs targeting various medical conditions.

Upstream product

• 629-05-0 n-octyne 
• 52914-23-5 4-iodophenethyl alcohol 
• 219307-07-0 4'-(2-hydroxyethyl)octanophenone 
• 122-79-2 Phenyl acetate 
• 162358-03-4 2-(4-octanoylphenyl)ethyl acetate 
• 103-45-7 acetic acid phenethyl ester 
• 111-64-8 n-octanoic acid chloride 
• 712223-57-9 acetic acid 2-[4-(trifluoromethanesulfonyloxy)phenyl]ethyl ester 
• 162358-04-5 acetic acid 2-(4-octylphenyl)ethyl ester 
• 58556-55-1 2-(4-hydroxyphenyl)ethyl acetate 
• 124-63-0 methanesulfonyl chloride 
• 162358-05-6 2-(4-Octylphenyl)ethyl alcohol 

Downstream Products

• 162358-08-9 diethyl 2-acetamido-2-[2-(4-octylphenyl)ethyl]malonate 
• 162359-55-9 fingolimod 
• 296282-46-7 2-amino-2-hydroxymethyl-4-(4-octyl-phenyl)-butyric acid 
• 296282-78-5 N-[1-cyano-1-hydroxymethyl-3-(4-octylphenyl)propyl]acetamide 
• 1027589-49-6 3-[2-(4-octyl-phenyl)-ethyl]-2-oxo-tetrahydro-furan-3-carboxylic acid 
• 249289-10-9 N-(1-hydroxy-2-(hydroxymethyl)-4-(4-octylphenyl) butan-2-yl) acetamide 
• 1027929-75-4 3-[2-(4-octyl-phenyl)-ethyl]-2-oxo-tetrahydro-furan-3-carboxylic acid ethyl ester 
• 296282-66-1 ethyl 2-acetamido-2-cyano-4-(4-octylphenyl)butyrate 
• 177259-57-3 2-Methoxycarbonylamino-2-[2-(4-octylphenyl)ethyl]-γ-butyrolactone 
• 177258-50-3 2-Methoxycarbonylamino-2-[2-(4-octylphenyl)ethyl]butane 1,4-diol 
• 162358-09-0 2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate 
• 177259-09-5 3-Acetamido-3-acetoxymethyl-5-(4-octylphenyl)pentyl acetate 
• 177260-26-3 2-amino-2-[2-(4-octylphenyl)ethyl]-5-(tetrahydro-2H-pyran-2-yloxy)pentanol 
• 1026240-85-6 2-[2-(4-octyl-phenyl)-ethyl]-2-[2-(tetrahydro-pyran-2-yloxy)-ethyl]-malonic acid diethyl ester 

Relevant articles and documents

Synthesis of FTY720 (Fingolimod) Derivatives Containing Serine Structure

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PROCESS FOR PREPARATION OF FINGOLIMOD

The present invention provides a process for preparation of fingolimod, a compound of Formula I or a pharmaceutically acceptable salt thereof, free of regioisomeric impurity compound of Formula IA

PREPARATION OF FINGOLIMOD AND ITS SALTS

The present application provide processes for the preparation of fingolimod and its pharmaceutically acceptable salts, process for the purification of fingolimod hydrochloride and process for the preparation of amorphous fingolimod hydrochloride.