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2195-44-0

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2195-44-0 Usage

General Description

2-BROMO-N-(4-FLUORO-PHENYL)-ACETAMIDE, also known as 2-bromo-4'-fluoroacetanilide, is an organic compound that belongs to the acetanilide class of chemicals. It is a derivative of acetanilide and contains a bromine atom and a 4-fluorophenyl group attached to the amide functional group. 2-BROMO-N-(4-FLUORO-PHENYL)-ACETAMIDE has applications in the pharmaceutical industry as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. It is also used in research and development as a building block in organic synthesis. The chemical properties and structure of 2-BROMO-N-(4-FLUORO-PHENYL)-ACETAMIDE make it a valuable tool in the creation of diverse compounds with potential therapeutic and agricultural properties.

Check Digit Verification of cas no

The CAS Registry Mumber 2195-44-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,1,9 and 5 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 2195-44:
(6*2)+(5*1)+(4*9)+(3*5)+(2*4)+(1*4)=80
80 % 10 = 0
So 2195-44-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H7BrFNO/c9-5-8(12)11-7-3-1-6(10)2-4-7/h1-4H,5H2,(H,11,12)

2195-44-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-bromo-N-(4-fluorophenyl)acetamide

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2195-44-0 SDS

2195-44-0Relevant articles and documents

Synthesis, anticancer, and computational studies of 1, 3, 4-oxadiazole-purine derivatives

Faisal, Shahla,Kamal, Shagufta,Parveen, Bushra,Rasool, Nasir,Rasul, Azhar,Raza, Zohaib,Shahzadi, Irum,Zahid, Faisal M.,Zahoor, Ameer F.,Zia-ur-Rehman, Muhammad

, p. 2782 - 2794 (2020)

Theophylline-7-acetic acid (acefylline) (3) and its derivatives are pharmacologically active compounds and generally recognized as bronchodilators for the treatment of respiratory diseases like acute asthma for over 70 years. In this article, synthesis of

Synthesis and Anti-Inflammatory Properties of Substituted 5-(Tetrahydro-4-phenyl-2H-pyran-4-yl)-4H-1,2,4-triazole-3-thiols

Arustamyan, Zh. S.,Margaryan,Aghekyan,Panosyan,Muradyan,Tumajyan

, p. 195 - 202 (2021/04/02)

Abstract: 5-(Tetrahydro-4-phenyl-2H-pyran-4-yl)-4H-1,2,4-triazole-3-thiol was synthesized by the reaction of 4-phenyltetrahydropyran-4-carbonyl chloride with thiosemicarbazide and subsequent cyclization of the resulting amide in the presence of KOH. The c

Pyrazoline tethered 1,2,3-triazoles: Synthesis, antimicrobial evaluation and in silico studies

Kumar, Anil,Kumar, Ashwani,Kumar, Lokesh,Lal, Kashmiri,Paul, Avijit Kumar

, (2021/08/03)

A new series of pyrazoline-amide linked 1,2,3-triazole hybrids was wisely designed and synthesized using 1,3-dipolar cycloaddition between pyrazoline linked alkynes and 2-bromo-N-arylacetamide. All the newly synthesized compounds were evaluated in vitro against different microbial strains viz. Escherichia coli, Bacillius subtilis, Staphylococcus aureus, Aspergillus niger, and Candida albicans. Pyrazoline linked terminal alkynes (4a–c) showed MIC = 0.062–0.078 μmol/mL against different bacterial and fungal strain. However, pyrazoline-amide linked 1,2,3-triazole hybrids (6a-6t) showed MIC = 0.0229–0.050 μmol/mL. Compound 6e exhibited better efficacy against E. coli and both the fungal strains compared to standard drugs used. Docking studies of the most potent compounds were carried out against bacterial DNA Gyr A and fungal 14α-steroldemethylase were also performed. The binding potential of 4a and 6e with both the target using molecular dynamics simulations was also investigated.

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