2196-95-4

Upstream product

• 1859-39-8 2-phenyl-N-hydroxyindole 
• 104-94-9 4-methoxy-aniline 

Downstream Products

• 110-86-1 pyridine 
• 1121-60-4 pyridine-2-carbaldehyde 
• 98-98-6 2-Picolinic acid 
• 50-00-0 formaldehyd 
• 5169-64-2 1,1'-dihydroxy-2,2'-diphenyl-3,3'-biindole 
• 2415-33-0 2,2'-diphenyl-1H,1'H-3,3'-biindole 
• 872-85-5 pyridine-4-carbaldehyde 
• 55-22-1 pyridine-4-carboxylic acid 
• 1121-58-0 4-(Methylamino)pyridine 
• 500-22-1 3-pyridinecarboxaldehyde 
• 59-67-6 nicotinic acid 
• 948-65-2 2-phenyl-indole 
• 123-39-7 N-Methylformamide 
• 64483-38-1 (2-methyl-2-phenyl-1,2-dihydroindol-3-ylidene)-phenylamine 

Relevant academic research and scientific papers

Radical intermediates in the peroxidation of indoles

2-Substituted and 1,2-disubstituted indoles react with m-chloroperbenzoic acid and hydrogen peroxide in the presence of acid or calcium chloride affording 2- and 3-(3-oxoindol-2-yl)indoles; whereas 2,3-disubstituted indoles, reacting with the same oxidant

Nucleophilic attack on the nitrone tautomeric form of 1-hydroxy-2- phenylindole

1-Hydroxy-2-phenylindole exists in solution in both hydroxylamine and nitrone tautomeric forms: the latter is able to add organomelallic compounds, forming stable indolinic aminoxyls, which were also prepared for comparison by an independent way. The title compound, after irradiation with a mercury lamp lead to a spin adduct. whose identification was proved by deuteration of 1-hydroxy-2-phenylindole at different levels. A mechanism similar to that invoked in the photoreaction of phenyltert-butylnitrone with nucleophiles has been proposed in order to interpret this behaviour. A macroscale irradiation of 1-hydroxy-2-phenylindole affording several compounds has also been carried out.

Direct Amination. Part 2. Reaction of 2-Phenylindole with Primary Aromatic Amines. A Chemical and Electrochemical Investigation

The reaction of 2-phenylindole with primary aromatic amines to form 2-phenyl-3-arylimino-3H-indoles, in the presence of N-chlorobenzotriazole, N-chloroisatin or lead tetraacetate, were also investigated by anodic oxidation.The chemical and electrochemical results suggest a mechanism involving an intermediate nitrenium ion, whose formation was demonstrated by an independent route.The reaction of 1-hydroxy-2-phenylindole with p-anisidine to form 2-phenyl-3-p-methoxyphenylimino-3H-indole 1-oxide, previously studied under anodic oxidation is here described in the presence of N-chlorobenzotriazole.

MOLECULAR COMPLEXES IN THE REACTIONS OF 1-HYDROXY-2-PHENYLINDOLE AND PHENYLAZOPYRIDINES

2- And 4-pyridines react with 1-hydroxy-2-phenylindole to give stable hydrogen-bonded molecular complexes. 3-pyridine give analogous complexes with 1,1'-dihydroxy-2,2'-dip

ELECTRON-TRANSFER PROCESSES: REACTIONS OF INDOLES WITH PERSULPHATE AND PEROXYACETIC ACID

Electron-rich aromatic N-heterocyclic compounds with a low oxidation potential promote the partial radicalisation of electrophiles having weak bonds (crypto-ions) via electron transfer.In particular, reactions of 1-hydroxy-2-phenylindole with persulphate or peroxyacetic acid lead to a mixture of bisindolyl nitroxide radical and nitrone, while in the case of 1-methyl-2-phenylindole the same reactions give the corresponding indoxyl derivative.