219639-04-0Relevant articles and documents
Concepts for ligand design in asymmetric catalysis: A study of chiral amino thiol ligands
Anderson, James C.,Cubbon, Rachel,Harding, Michael,James, Daniel S.
, p. 3461 - 3490 (2007/10/03)
A series of new chiral sulfur-nitrogen chelate ligands, derived from amino acids, has been synthesised rationally. Fruitless experiments into catalytic asymmetric conjugate additions and desymmetrisation of meso- epoxides led us to analyse our ligands in
The importance of nitrogen substituents in chiral amino thiol ligands for the asymmetric addition of diethylzinc to aromatic aldehydes
Anderson, James C.,Harding, Michael
, p. 393 - 394 (2007/10/03)
A new series of N,S-chelate ligands derived from (S)-valine, which possess the capability of a stereogenic nitrogen donor atom, are catalysts for the addition of diethylzinc to aromatic aldehydes and gave the product secondary alcohols in up to 82% ee.
