219717-84-7Relevant academic research and scientific papers
Synthesis of substituted (D)-phenylalanine derivatives by regioselective reduction of enantiomerically pure cis-2,3-disubstituted aziridines
Chang, Jae-Won,Bae, Jae Hyun,Shin, Seong-Ho,Park, Chan Sun,Choi, Daeock,Lee, Won Koo
, p. 9193 - 9196 (1998)
Various N-(R)-(+)-(α-methylbenzyl)-(2R,3R)-distributed aziridines were prepared by intramolecular cyclization. The regioselective reduction of the ring C(3)-N bond in the presence of (Boc)2O by catalytic hydrogenation with atmospheric pressure of hydrogen provides (D)-phenylalaninol analogues in good yields.
