219782-24-8

Basic information

• Product Name: {[1-(2-Nitro-phenyl)-meth-(Z)-ylidene]-amino}-acetic acid methyl ester
• CAS NO: 219782-24-8
• Molecular Weight: 222.2
• Mol File: 219782-24-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: {[1-(2-Nitro-phenyl)-meth-(Z)-ylidene]-amino}-acetic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: {[1-(2-Nitro-phenyl)-meth-(Z)-ylidene]-amino}-acetic acid methyl ester(219782-24-8)
• EPA Substance Registry System: {[1-(2-Nitro-phenyl)-meth-(Z)-ylidene]-amino}-acetic acid methyl ester(219782-24-8)

Safety Data

• Hazardous Substances Data: 219782-24-8(Hazardous Substances Data)

Upstream product

• 5680-79-5 glycine ethyl ester hydrochloride 
• 552-89-6 2-nitro-benzaldehyde 

Downstream Products

• 1331731-50-0 (1R,3S,3aR,6aS)-methyl 3-(2-nitrophenyl)-4,6-dioxo-5-phenyloctahydropyrrolo-[3,4-c]pyrrole-1-carboxylate 
• 345201-73-2 {[2-(2-{(2-tert-butoxycarbonylamino-ethyl)-[(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-acetyl]-amino}-acetylamino)-benzyl]-[(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-acetyl]-amino}-acetic acid methyl ester 
• 345201-78-7 {[2-(2-{(2-tert-butoxycarbonylamino-ethyl)-[(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-acetyl]-amino}-acetylamino)-benzyl]-[(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-acetyl]-amino}-acetic acid 
• 345201-60-7 methyl N-(2-nitrobenzyl)-N-(thymin-1-ylacetyl)glycinate 
• 345201-64-1 methyl N-(2-aminobenzyl)-N-(thymin-1-ylacetyl)glycinate 
• 85313-33-3 methyl N-(2-nitrobenzyl)glycinate hydrochloride 
• 179686-64-7 methyl N-(2-nitrobenzyl)glycinate 

Relevant articles and documents

Metal-free asymmetric 1,3-dipolar cycloaddition of N-arylmaleimides to azomethine ylides catalyzed by chiral tertiary amine thiourea

The first metal-free asymmetric 1,3-dipolar cycloaddition of N-arylmaleimides to azomethine ylides catalyzed by chiral tertiary amine thiourea to form multiply substituted pyrrolidines in excellent yields (up to 89%) and enantioselectivities (up to 96% ee) is presented. This procedure allows a rapid diversity-oriented synthesis of chiral pyrrolidine derivatives with high optical purity. A series of bifunctional thiourea catalysts were applied for the first time to the highly asymmetric 1,3-dipolar cycloaddition of N-arylmaleimides to azomethine ylides togive the products in excellent yields (up to 89%) and enantioselectivities (up to 96% ee).