N-(4-chloro-phenyl)-glycine amide, also known as chlorambucil, is an organic compound with the chemical formula C8H8ClNO2. It is a derivative of phenylglycine, featuring a 4-chlorophenyl group attached to the nitrogen atom. N-(4-chloro-phenyl)-glycine amide is primarily used as an anticancer drug, specifically as an alkylating agent. It works by inhibiting DNA synthesis and RNA function, thereby disrupting cell division and ultimately leading to cell death. Chlorambucil is particularly effective in treating chronic lymphocytic leukemia, Hodgkin's lymphoma, and other malignancies. Its chemical structure and mechanism of action make it a valuable tool in oncology, despite its potential side effects and the need for careful administration.
21979-12-4
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Basic information
- Product Name: N-(4-chloro-phenyl)-glycine amide
- Synonyms: N-(4-chloro-phenyl)-glycine amide
- CAS NO:21979-12-4
- Molecular Formula:
- Molecular Weight: 184.625
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: N-(4-chloro-phenyl)-glycine amide(CAS DataBase Reference)
- NIST Chemistry Reference: N-(4-chloro-phenyl)-glycine amide(21979-12-4)
- EPA Substance Registry System: N-(4-chloro-phenyl)-glycine amide(21979-12-4)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 21979-12-4(Hazardous Substances Data)
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Check Digit Verification of cas no
The CAS Registry Mumber 21979-12-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,9,7 and 9 respectively; the second part has 2 digits, 1 and 2 respectively.Calculate Digit Verification of CAS Registry Number 21979-12:
(7*2)+(6*1)+(5*9)+(4*7)+(3*9)+(2*1)+(1*2)=124
124 % 10 = 4
So 21979-12-4 is a valid CAS Registry Number.
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N-(4-chloro-phenyl)-glycine amide
