219797-98-5Relevant academic research and scientific papers
Synthesis of cotelomers derived from tris(hydroxymethyl)acrylamidomethane (THAM) bearing cytosine arabinoside moieties. Preliminary investigation of their biological activity
Contino, Christiane,Ollier, Monique,Maurizis, Jean Claude,Lacombe, Jean Michel,Pucci, Bernard
, p. 9049 - 9052 (1996)
The telomerization of tris(hydroxymethyl)acrylamidomethane (THAM) and cytosine arabinoside (Ara-C) polymerizable derivatives in the presence of transfer reagent such as alkane or perfluoroalkane thiol is described. The cytotoxic activities of these differ
Synthesis of new cotelomers derived from tris(hydroxymethyl) aminomethane bearing arabinofuranosylcytosine moieties. Preliminary results on their in vitro and in vivo antitumoral activities
Contino, Christiane,Maurizis, Jean-Claude,Ollier, Monique,Rapp, Maryse,Lacombe, Jean-Michel,Pucci, Bernard
, p. 809 - 816 (2007/10/03)
As an approach to the development of drug delivery systems, a new class of low macromolecular carriers called telomers bearing both antitumor agent such as arabinofuranosylcytosine (Ara-C) and galactose moieties were synthesized. These compounds were prep
