Synthesis of cotelomers derived from tris(hydroxymethyl)acrylamidomethane (THAM) bearing cytosine arabinoside moieties. Preliminary investigation of their biological activity

DOI: 10.1016/S0040-4039(96)02122-3

Source and publish data:

Tetrahedron Letters p. 9049 - 9052 (1996)

Update date:2022-09-26

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Authors:

Contino, Christiane

Ollier, Monique

Maurizis, Jean Claude

Lacombe, Jean Michel

Pucci, Bernard

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Article abstract of DOI:10.1016/S0040-4039(96)02122-3

The telomerization of tris(hydroxymethyl)acrylamidomethane (THAM) and cytosine arabinoside (Ara-C) polymerizable derivatives in the presence of transfer reagent such as alkane or perfluoroalkane thiol is described. The cytotoxic activities of these differ

Full text of DOI:10.1016/S0040-4039(96)02122-3

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