219840-91-2Relevant academic research and scientific papers
Aryl- and arylamino- substituted heterocycles as corticotropin releasing hormone antagonists
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, (2008/06/13)
Corticotropin releasing factor (CRF) antagonists of formula I: and their use in treating psychiatric disorders and neurological diseases, anxiety-related disorders, post-traumatic stress disorder, supranuclear palsy and feeding disorders as well as treatment of immunological, cardiovascular or heart-related diseases and colonic hypersensitivity associated with psychopathological disturbance and stress in mammals.
4-Aryl-2-anilinopyrimidines as corticotropin-releasing hormone (CRH) antagonists
Cocuzza, Anthony J.,Hobbs, Frank W.,Arnold, Charles R.,Chidester, Dennis R.,Yarem, Jerry A.,Culp, Steven,Fitzgerald, Lawrence,Gilligan, Paul J.
, p. 1057 - 1062 (2007/10/03)
A series of 4-aryl-2-(N-ethylanilino)pyrimidines has been synthesized as corticotropin-releasing hormone (CH) inhibitors. The effect of substitution on each aromatic ring on receptor binding was investigated.
