Welcome to LookChem.com Sign In|Join Free
  • or
(E)-4-((3-(Pyridin-3-yl)acrylaMido)Methyl)benzoic acid is an organic compound that serves as a key intermediate in the synthesis of chidamide, a novel histone deacetylase (HDAC) inhibitor. (E)-4-((3-(pyridin-3-yl)acrylaMido)Methyl)benzoic acid plays a crucial role in the development of pharmaceuticals targeting epigenetic regulation for various therapeutic applications.

219964-34-8

Post Buying Request

219964-34-8 Suppliers

Recommended suppliers

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

219964-34-8 Usage

Uses

Used in Pharmaceutical Industry:
(E)-4-((3-(Pyridin-3-yl)acrylaMido)Methyl)benzoic acid is used as a reagent for the synthesis of chidamide, a new histone deacetylase (HDAC) inhibitor. HDAC inhibitors, such as chidamide, have gained significant attention in the pharmaceutical industry due to their potential role in the treatment of various diseases, including cancer, by modulating gene expression and altering chromatin structure.

Check Digit Verification of cas no

The CAS Registry Mumber 219964-34-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,9,9,6 and 4 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 219964-34:
(8*2)+(7*1)+(6*9)+(5*9)+(4*6)+(3*4)+(2*3)+(1*4)=168
168 % 10 = 8
So 219964-34-8 is a valid CAS Registry Number.

219964-34-8Relevant academic research and scientific papers

Benzamide Derivative as Histone Deacetylase Inhibitor with Potent Differentiation and Anti-Proliferation Activity

-

Paragraph 0038; 0039, (2017/12/27)

The present invention is related to the preparation and pharmaceutical use of novel benzamide derivatives as defined in the specification of formula (I) as histone deacetylase inhibitors (HDACI), their preparations and the methods of using these compounds

Histone deacetylase inhibitors and uses thereof

-

Page/Page column 27, (2011/07/06)

The present invention discloses a group of histone deacetylase inhibitors and use thereof. The histone deacetylase inhibitors are useful in the treatment of malignant tumors and the diseases associated with differentiation and proliferation. The histone deacetylase inhibitors are the compounds represented by the following formula or salts thereof:

HISTONE DEACETYLASE INHIBITORS AND USES THEREOF

-

Page/Page column 28, (2011/04/25)

The present invention discloses a group of histone deacetylase inhibitors and use thereof. The histone deacetylase inhibitors are useful in the treatment of malignant tumors and the diseases associated with differentiation and proliferation. The histone deacetylase inhibitors are the compounds represented by the following formula or salts thereof

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 219964-34-8