21997-97-7Relevant academic research and scientific papers
Efficient synthesis of tetrahydro-b-carbolin-1-one and dihydroisoquinolin- 1-one derivatives as versatile Intermediates
Judd, Katie E.,Mahon, Mary F.,Caggiano, Lorenzo
experimental part, p. 2809 - 2817 (2010/01/21)
An efficient one-pot procedure is described in which an isocyanate intermediate, generated from the corresponding carboxylic acid by a modified Curtius rearrangement, is captured by a tethered aromatic ring in the presence of BF3?OEt2 to generate various
A SYNTHESIS OF HETEROCYCLIC FUSED ISOQUINOLINES THROUGH N-ACYLIMINIUM ION INTERMEDIATES
Kano, Shinzo,Yuasa, Yoko,Shibuya, Shiroshi
, p. 883 - 890 (2007/10/02)
Conversion of terminal olefin to formyl group by ozonolysis was applied to a new generation of N-acyliminium ions and several kinds of hetercyclic fused isoquinolines were prepared.
AN ENANTIOSELECTIVE SYNTHESIS OF 1-(α-HYDROXYALKYL)-1,2,3,4-TETRAHYDROISOQUINOLINES THROUGH OPTICALLY ACTIVE N-OXAACYLIMINIUM ION INTERMEDIATES
Kano, Shinzo,Yuasa, Yoko,Shibuya, Shiroshi
, p. 395 - 398 (2007/10/02)
An enantioselective synthesis of 1S-(1'S-hydroxyethyl)- 1S-(1'S-hydroxybenzyl)- and 1R-(1'R-hydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline was achieved by reductive cleavage of the oxazolidinone ring of the correspponding 1-substituted oxazoloisoqui
A NEW GENERATION OF α-OXA-ACYLIMINIUM IONS AND AN APPLICATION TO A SYNTHESIS OF OXAZOLOISOQUINOLINE AND RELATED COMPOUNDS
Kano, Shinzo,Yuasa, Yoko,Yokomatsu, Tsutomu,Shibuya, Shiroshi
, p. 1475 - 1476 (2007/10/02)
The carbamates, obtained by the reaction of the azide with ethyl glycolate and ethyl lactate, were reduced with i-Bu2AlH and the reduction products were treated with formic acid to give the corresponding oxazoloisoquinolines.By this method, the thi
