22007-37-0Relevant academic research and scientific papers
A novel three-component reaction between isocyanides, alcohols or thiols and elemental sulfur: A mild, catalyst-free approach towards O-thiocarbamates and dithiocarbamates
Németh, András Gy?rgy,Keseru, Gy?rgy Miklós,ábrányi-Balogh, Péter
supporting information, p. 1523 - 1533 (2019/08/07)
A new multicomponent reaction has been developed between isocyanides, sulfur and alcohols or thiols under mild reaction conditions to afford O-thiocarbamates and dithiocarbamates in moderate to good yields. The one-pot reaction cascade involves the formation of an isothiocyanate intermediate, thus a catalyst-free synthesis of isothiocyanates, as valuable building blocks from isocyanides and sulfur is proposed, as well. The synthetic procedure suits the demand of a modern organic chemist, as it tolerates a wide range of functional groups, it is atom economic and easily scalable.
Glycosyl alkoxythioimidates as building blocks for glycosylation: A reactivity study
Ranade, Sneha C.,Demchenko, Alexei V.
, p. 115 - 122 (2015/02/19)
Structural modifications of the leaving group of S-glycosyl O-methyl phenylcarbamothioates (SNea) involving change of substituents that express different electronic effects led to a better understanding of how the reactivity of these glycosyl donors can b
REACTIONS OF 1-CHLOROALKYL ISOCYANATES WITH THIOURETHANES
Vovk, M. V.,Davidyuk, Yu. N.,Chernega, A. N.,Tsymbal, I. F.,Samarai, L. I.
, p. 1635 - 1643 (2007/10/02)
1-Chloroalkyl isocyanates react with thiourethanes to gives N-acylation products, namely, N-(N-alkylidenaminocarbonyl)thiourethanes, which exist in solution in tautomeric equilibrium with S-(1-isocyanatoalkyl)isothiourethanes.These tautomeric transformation occur in the C=N-C azaallylic system involving a new anionotropic migrant, namely, the thiocarbamyl group.The reactions of these tautomeric compounds with water, alcohols, phenol, and primary amines proceed with the participation of the azomethine form, while the reactions with secondary amines involve the isocyanate form.
