220096-40-2

Basic information

• Product Name: 1,2-bis[di(3',5'-diformylphenyl)phosphanyl]ethane
• Synonyms: 1,2-bis[di(3',5'-diformylphenyl)phosphanyl]ethane
• CAS NO: 220096-40-2
• Molecular Weight: 622.507
• Mol File: 220096-40-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,2-bis[di(3',5'-diformylphenyl)phosphanyl]ethane(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-bis[di(3',5'-diformylphenyl)phosphanyl]ethane(220096-40-2)
• EPA Substance Registry System: 1,2-bis[di(3',5'-diformylphenyl)phosphanyl]ethane(220096-40-2)

Safety Data

• Hazardous Substances Data: 220096-40-2(Hazardous Substances Data)

Upstream product

• 220096-20-8 1-Bromo-3,5-bis(dimethoxymethyl)benzene 
• 120173-41-3 5-bromobenzene-1,3-dicarbaldehyde 
• 51760-21-5 dimethyl 5-bromoisophthalate 
• 51760-22-6 5-bromo-1,3-dihydroxymethylbenzene 
• 99-27-4 dimethyl 5-aminoisophthalate 
• 220096-27-5 1,2-bis[di[3',5'-bis(dimethoxymethyl)phenyl]phosphanyl]ethane 

Relevant articles and documents

Enantioselective catalysis; 123: Octaaldehyde type chelating ligands - A divergent synthesis approach to easily tunable expanded ligands for enantioselective catalysis

A broad range of optically active two-layer phosphanes was obtained by a divergent reaction sequence. Chirality was introduced into the ligands in the last step by easily performed Schiff base condensation of primary amines from the 'chiral pool' and achiral octaaldehydes containing a bisphosphane core. The two achiral precursors are 1,2-ethylene- and o-phenylene-bridged bisphosphanes with four 3,5-dicarbaldehyde-substituted phenyls, synthesized in six steps. The resulting octaimine ligands have been used in Rh, Pd and Ni complexes in several model reactions of enantioselective catalysis giving low optical inductions.