22014-78-4Relevant academic research and scientific papers
Biological evaluation of 1-alkyl-3-phenylthioureas as orally active HDL-elevating agents
Coppola, Gary M.,Damon, Robert E.,Eskesen, J. Bruce,France, Dennis S.,Paterniti Jr., James R.
, p. 113 - 117 (2006)
A series of 1-alkyl-3-phenylthiourea analogues were prepared and evaluated as HDL- and Apo A-I-elevating and triglyceride-lowering agents. Several derivatives were superior to gemfibrozil (1). The optimal analogue 8d (HDL376) was shown to raise HDL choles
