220230-97-7

Upstream product

• 53560-33-1 3,4,5-trimethoxyphenylacetylene 
• 143287-98-3 3,4,5-trimethoxyphenyl trifluoromethanesulfonate 
• 2675-79-8 1-bromo-3,4,5-trimethoxybenzene 
• 994-71-8 bis(tributylstannyl)acetylene 
• 142-45-0 Acetylenedicarboxylic acid 

Downstream Products

• 220230-99-9 dimethyl 4,5-bis(3,4,5-trimethoxyphenyl)-1,2-diazine-3,6-dicarboxylate 
• 52605-12-6 1,2-bis(3,4,5-tri-methoxyphenyl)ethane-1,2-dione 
• 220231-07-2 3,4-bis(3,4,5-trimethoxyphenyl)-1-<2-(4-methoxyphenyl)ethyl>pyrrole-2,5-biscarboxamide 
• 220231-09-4 E,Z-3,4-bis(3,4,5-trimethoxyphenyl)-1-<2-(4-methoxyphenyl)ethyl>pyrrole-2,5-biscarboxamide 
• 220231-11-8 Z,Z-3,4-bis(3,4,5-trimethoxyphenyl)-1-<2-(4-methoxyphenyl)ethyl>pyrrole-2,5-biscarboxamide 
• 219783-09-2 3,4-bis(3,4,5-trimethoxyphenyl)-1-<2-(4-methoxyphenyl)ethyl>pyrrole-2,5-dicarboxylic acid 
• 220231-03-8 dimethyl 3,4-bis(3,4,5-trimethoxyphenyl)-1-<2-(4-methoxyphenyl)ethyl>pyrrole-2,5-dicarboxylate 
• 220231-01-6 3,4-bis-(3,4,5-trimethoxyphenyl)-1H-pyrrole-2,5-dicarboxylic acid dimethyl ester 

Relevant academic research and scientific papers

"Double-concave" graphene: Permethoxylated hexa-peri- hexabenzocoronene and its cocrystals with hexafluorobenzene and fullerene

Extremely nonplanar permethoxylated hexa-peri-hexabenzocoronene can be prepared by using a facile ferric chloride cyclodehydrogenation procedure. The combination of a rigid "double-concave" aromatic core with 18 flexible methoxy groups at the periphery ma

Space-conjugated organic molecule based on hexaarylbenzene skeleton and preparation and application thereof

The invention belongs to the technical field of organic electronics, and discloses a space-conjugated organic molecule based on a hexaarylbenzene skeleton and preparation and application thereof. Thespace-conjugated organic molecular structure based on th

Total syntheses of ningalin A, lamellarin O, lukianol A, and permethyl storniamide A utilizing heterocyclic azadiene Diels - Alder reactions

Concise, efficient total syntheses of ningalin A (1), lamellarin O (2), lukianol A (3), and permethyl storniamide A (5) are detailed on the basis of a common heterocyclic azadiene Diels-Alder strategy (1,2,4,5-tetrazine → 1,2-diazine → pyrrole) ideally suited for construction of the densely functionalized pyrrole cores found in the three classes of marine natural products. Examination of the natural products and a number of synthetic intermediates revealed that some including lamellarin O (2) and lukianol A (3) exhibit modest cytotoxic activity against both wild-type and multidrug- resistant tumor cell lines. Fundamentally more important, a new class of agents including permethyl storniamide A (5) and its precursor 30, which lack inherent cytotoxic activity, are disclosed which reverse the multidrug- resistant (MDR) phenotype, resensitizing a human colon cancer cell line (HCT116/VM46) to vinblastine and doxorubicin at lower doses than the prototypical agent verapamil.