220239-29-2Relevant academic research and scientific papers
Chemoselective reduction of a lactam carbonyl group in the presence of a gem-dicarboxylate by sodium borohydride and iodine: A facile entry to N-aryl trisubstituted pyrroles
Haldar, Pranab,Ray, Jayanta K.
, p. 8229 - 8231 (2003)
Several N-aryl γ-lactam gem dicarboxylates were chemoselectively reduced to cyclic amine diesters by using sodium borohydride-iodine system. The reduction in all cases was completed within 2.5 h after refluxing in THF. The cyclic amine products were isolated after aqueous (acidic) workup in good yields. Hydrolytic decarboxylation followed by dehydrogenation produced N-aryl carboethoxy pyrroles.
Synthesis of some thieno gamma lactam monocarboxylic acids with high antibacterial activity: A new look at an old molecular system
Kar, Gandhi K.,Roy, Bidhan C.,Adhikari, Sujit Das,Ray, Jayanta K.,Brahma, Nitosh K.
, p. 2397 - 2403 (1998)
Synthesis and antibacterial activity of some novel monocyclic thienyl gamma lactams are reported. The compounds have been synthesized by a two-step process consisting of, first, intermolecular Michael addition, followed by intramolecular amidification bet
