Synthesis of some thieno gamma lactam monocarboxylic acids with high antibacterial activity: A new look at an old molecular system

Article abstract of DOI:10.1016/S0968-0896(98)80015-1

Synthesis and antibacterial activity of some novel monocyclic thienyl gamma lactams are reported. The compounds have been synthesized by a two-step process consisting of, first, intermolecular Michael addition, followed by intramolecular amidification bet