220272-09-3Relevant academic research and scientific papers
Enantiospecific formal total synthesis of iriomoteolide 3a
Kumar, S. Mothish,Prasad, Kavirayani R.
, p. 3431 - 3439 (2015/02/19)
A formal total synthesis of the marine macrolide iriomoteolide 3a is described. Salient features of the synthesis include the elaboration of a β-keto phosphonate derived from d-(-)-tartaric acid and the extension of a chiral butyrolactone derived from L-g
Synthetic studies toward potent cytotoxic agent amphidinolide B: Synthesis of the C8-C18 fragment
Chakraborty,Thippeswamy
, p. 150 - 152 (2007/10/03)
A practical synthesis of the C8-C18 fragment 1 of amphidinolide B is described in which the Stille coupling method was employed to construct the trisubstituted C28=C13-C14=C15 's-cis-1,3-diene' moiety from suitably functionalized vinyl iodide (4) and vinyl stannane (5) fragments, the former being prepared from an acetylene precursor using Negishi's carboalumination/iodination method.
