220287-26-3

Upstream product

• 213838-29-0 diethyl 2-(2-(4-chlorophenyl)-2-oxoethyl)malonate 
• 124500-02-3 α-cyano-β-(p-chlorobenzoyl)propionic acid 

Downstream Products

• 158977-76-5 ethyl 6-(4-chlorophenyl)-3-oxo-2,3-dihydropyridazine-4-carboxylate 
• 220287-27-4 6-(4-chlorophenyl)-3-oxo-2,3-dihydropyridazine-4-carboxylic acid 
• 220287-28-5 ethyl 3-chloro-6-(4-chlorophenyl)-pyridazine-4-carboxylate 

Relevant academic research and scientific papers

Synthesis and pharmacological screening of pyrazolo[3,4-c]pyridazine derivatives

Ethyl 3-chloro-6-(4-chlorophenyl)-pyridazine-4-carboxylate [VII] was cyclized with some nucleophilic reagents (hydrazine hydrate or N-monosubstituted hydrazines) to the new derivatives of pyrazolo[3,4-c]pyridazine [IXa-d]. The structures of the novel compounds were confirmed by elemental and spectral analyses. The effect of several synthesized derivatives on the central nervous system was studied.