220299-99-0Relevant academic research and scientific papers
Synthesis of 1,3,4-oxadiazole derivatives with anticonvulsant activity and their binding to the GABAA receptor
Lei, Kang,Li, Guangyong,Li, Jun,Liu, Hui,Liu, Renmin,Quan, Zheshan,Wang, Shiben,Wang, Xuekun
, (2020)
In this study, a series of 1,3,4-oxadiazole derivatives (5a-s, 10a-s, and 16a-d) were designed and synthesized using maximal electroshock (MES) and subcutaneous pentylenetetrazole (scPTZ) models, to test the anticonvulsant activity of the target compounds
Design and synthesis of newer potential 4-(N-acetylamino)phenol derived piperazine derivatives as potential cognition enhancers
Piplani, Poonam,Danta, Chhanda Charan
, p. 64 - 73 (2015/05/20)
A series of novel hybrids has been designed, synthesized and evaluated for cognition enhancing activities through the inhibition of acetylcholinesterase (AChE) and by passive avoidance mouse model. All the compounds showed excellent AChE inhibition activi
Substituted piperidine compounds useful as modulators of chemokine receptor activity
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Page/Page column 81, (2008/06/13)
The invention provides compounds of formula (I) wherein R1, R2, R3, R6, Z, Q, m, n, X1, X2, X3, X4 and T are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them, and their use in therapy, especially for the treatment of chemokine receptor related diseases and conditions
Synthesis and local anaesthetic activity of 2-substituted-N-(2-diethylaminoethyl)-acetamides
Jindal, Dharam Paul,Coumar, Mohane S.,Singh, Babita,Mohammed Ismail, Mohammed Muhiyiden,Zambare, Girish Nilkanth,Bodhankar, Subhash Laxmanrao
, p. 34 - 39 (2007/10/03)
The synthesis of 2-substituted-N-(2-diethylaminoethyl)acetamide oxalates (6a, 6b) and the evaluation of their in vivo local anaesthetic activities are described. The compounds 6a and 6b were obtained starting from 4-acetamidophenol and 1-naphthol, respect
