84501-28-0

Basic information

• Product Name: 4-TERT-BUTYL-2,6-DIFORMYLPHENOL
• Synonyms: 5-(TERT-BUTYL)-2-HYDROXYISOPHTHALALDEHYDE;AKOS BC-1732;4-TERT-BUTYL-2,6-DIFORMYLPHENOL;5-(1,1-DIMETHYLETHYL)-2-HYDROXY-1,3-BENZENEDICARBOXALDEHYDE;4-tert-Butyl-2,6-diformylphenol,5-(1,1-Dimethylethyl)-2-hydroxy-1,3-benzenedicarboxaldehyde;5-(tert-Butyl)-2-hydroxybenzene-1,3-dicarboxaldehyde, 4-(tert-Butyl)-2,6-diformylphenol;4-tert-Butyl-2,6-diforMylphenol 96%;4-tert-Butyl-2,6-diformylphenol
• CAS NO: 84501-28-0
• Molecular Formula: C₁₂H₁₄O₃
• Molecular Weight: 206.24
• Product Categories: Aldehydes;Building Blocks;C10-C12;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks
• Mol File: 84501-28-0.mol
• Article Data: 22

Chemical Properties

• Melting Point: 99-103 °C(lit.)
• Boiling Point: 267.8°C at 760 mmHg
• Flash Point: 130°C
• Appearance: /
• Density: 1.159g/cm³
• Vapor Pressure: 0.00484mmHg at 25°C
• Refractive Index: 1.589
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 6.61±0.23(Predicted)
• CAS DataBase Reference: 4-TERT-BUTYL-2,6-DIFORMYLPHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-TERT-BUTYL-2,6-DIFORMYLPHENOL(84501-28-0)
• EPA Substance Registry System: 4-TERT-BUTYL-2,6-DIFORMYLPHENOL(84501-28-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 84501-28-0(Hazardous Substances Data)

Usage

Uses

1. Used as a key intermediate for the production of a BODIPY chemodosimetric sensor for cyanide ions. 2. Used as a key intermediate for a Pro-ligand in bimetallic catalysis.

General Description

4-tert-Butyl-2,6-diformylphenol can be prepared from 4-tert-butylphenol and hexamethylenetetramine.

InChI:InChI=1/C12H14O3/c1-12(2,3)10-4-8(6-13)11(15)9(5-10)7-14/h4-7,15H,1-3H3

Upstream product

• 2203-14-7 4-tert-butyl-2,5-bis(hydroxymethyl)phenol 
• 50-00-0 formaldehyd 
• 98-54-4 para-tert-butylphenol 
• 94516-52-6 5-tert-butyl-1,3-bis-hydroxymethyl-2-(toluene-4-sulfonyloxy)-benzene 
• 100-97-0 hexamethylenetetramine 
• 94516-53-7 Toluene-4-sulfonic acid 4-tert-butyl-2,6-diformyl-phenyl ester 

Downstream Products

• 84501-10-0 Cu⁽²⁺⁾*((CH₃)3CC₆H₂O(CHN)(CHO))2(CH₂CH₂CH₂)^(2-) = Cu((CH₃)3CC₆H₂O(CHN)(CHO))2(CH₂CH₂CH₂) 
• 210417-68-8 2-methoxy-5-tert-butyl-1,3-benzenedicarboxaldehyde 
• 1227783-54-1 5M₅M-terbut 
• 312962-45-1 2-(N,N-dimethylthiocarbamato-S)-5-tert-butylisophthalaldehyde 
• 946409-81-0 1,4-bis[(4-tert-butyl-2-formylphenyl)ethynyl]-2,3-bis[(4-tert-butyl-2,6-diformylphenyl)ethynyl]benzene 
• 946409-80-9 5-tert-butyl-1,3-diformyl-2-iodobenzene 
• 713524-75-5 4-(tert-butyl)-2,6-diformylphenyl trifluoromethanesulfonate 

Relevant articles and documents

Proton-template synthesis, structure, and characterization of a Robson- type macrocycle with a totally π-conjugated system

π-Conjugated (1-4) and partially reduced (5) macrocyclic Schiff bases have been obtained by proton-template condensation of 2,6-diformyl-4-R1- phenol (R1 = Me, t-Bu) with 1,2-diamino-4,5-R2-benzene (R2 = H, Me).

Antioxidant, DNA interaction, molecular docking and cytotoxicity studies of aminoethylpiperazine-containing macrocyclic binuclear copper(II) complexes

A series of new macrocyclic binuclear copper(II) complexes of the type [Cu2L1–5(ClO4)](ClO4) (1–5) were synthesized by template condensation between precursor compounds 2,6-bis(4-aminoethylpiperazin-1-ylmethyl)-

Preparation method and application of mercaptan fluorescence probe based on coumarin

The invention discloses a preparation method and application of a mercaptan fluorescence probe based on coumarin. The preparation method includes: coumarin and p-tert-butylphenol dialdehyde are used as raw materials to synthesize a bis-Schiff base coumarin derivative (compound I), the compound I has strong fluorescence, and the compound I is coordinated with copper ions to prepare coumarin-copper ion (II) complex, namely the mercaptan fluorescence probe I-Cu (II). Due to the influence of the paramagnetism of Cu2+ and photoinduction electron transfer effect, the fluorescence of the compound I is quenched; sulfur atoms in compounds such as mercapto-amino acid and derivatives such as glutathione thereof and Cu2+ have a strong coordination effect, the competitive coordination effect allows the copper ions in the coumarin-copper ion (II) complex to be taken away by the mercapto-amino acid and the derivatives thereof so as to regenerate the compound I, and the fluorescence of the compound I is restored. Accordingly, a method for fast and simply detecting mercaptan compounds is built.