220369-79-9

Upstream product

• 63-91-2 L-phenylalanine 
• 6066-82-6 1-hydroxy-pyrrolidine-2,5-dione 
• 90508-20-6 N-allyloxycarbonyl-(S)-phenylalanate 

Downstream Products

• 1343407-41-9 C₅₉H₆₉N₇O₁₄ 
• 1343407-40-8 C₄₉H₅₈N₆O₁₁ 
• 1343407-39-5 C₅₃H₆₂N₆O₁₃ 
• 1343407-38-4 C₅₃H₆₄N₆O₁₃ 
• 1343407-37-3 C₅₅H₆₆N₆O₁₄ 
• 1343407-89-5 Alloc-Phe-Lys(Boc)-PABOH 
• 220369-81-3 alloc-Phe-Phe 

Relevant academic research and scientific papers

PYRROLOBENZODIAZEPINES AND CONJUGATES THEREOF

Conjugates and compounds for making conjugates which are PBD molecules linked via the N10 position are disclosed, along with the use of the conjugates for treating proliferative diseases, including cancer.

Cathepsin B-sensitive dipeptide prodrugs. 1. A model study of structural requirements for efficient release of doxorubicin

A series of lysosomal protease-sensitive peptides attached to doxorubicin (DOX) was prepared as model substrates for internalizing anticancer immunoconjugates and potential antimetastasis prodrugs. Rates of cathepsin B-mediated release of free drug was measured for each, and human plasma stabilities for representative examples.