220601-50-3Relevant academic research and scientific papers
The design, synthesis, and evaluation of novel conformationally rigid analogues of sialyl Lewis(x)
Murphy, Paul V.,Hubbard, Rod E.,Manallack, David T.,Wills, Ruth E.,Montana, John G.,Taylor, Richard J. K.
, p. 2421 - 2439 (2007/10/03)
The design and synthesis of a series of analogues of sialyl Lewis(x) (1) which incorporate conformationally rigid tetralin and naphthalene ring systems (2-4) has led to novel compounds which have similar potency to 1 as inhibitors of cell adhesion. Copyright (C) 1998 Elsevier Science Ltd.
The synthesis of novel structural analogues of sialyl Lewis(x)
Murphy, Paul V.,Hubbard, Rod E.,Manallack, David T.,Montana, John G.,Taylor, Richard J. K.
, p. 3273 - 3276 (2007/10/03)
The synthesis of conformationally rigid tetralin-based mimics of the tetrasaccharide sialyl Lewis(x) are described. Palladium catalysed coupling reactions are employed in the key synthetic steps.
