220623-25-6

Upstream product

• 220623-03-0 (1S,1aR,1bS,4R,5aS)-5-Oxo-4-phenyl-hexahydro-3-oxa-4a-aza-cyclopropa[a]pentalene-1-carboxylic acid methyl ester 
• 220623-04-1 (1R,1aR,1bS,4R,5aS)-5-Oxo-4-phenyl-hexahydro-3-oxa-4a-aza-cyclopropa[a]pentalene-1-carboxylic acid methyl ester 
• 220623-23-4 (1R,2S,5S,6R)-3-aza-3-benzyl-6-methoxycarbonylbicyclo<3.1.0>hexyl-2-methanol 
• 892865-81-5 C₈H₁₃NO₃ 
• 186429-20-9 (S,E)-methyl 4-((tert-butoxycarbonyl)amino)-5-((tert-butyldiphenylsilyl)oxy)pent-2-enoate 
• 103201-79-2 (3R,7aS)-3-phenyl-tetrahydro-pyrrolo[1,2-c]oxazol-5-one 
• 134107-65-6 (3R,7aS)-3-phenyl-3,7a-dihydro-1H-pyrrolo[1,2-c]oxazol-5-one 
• 220623-24-5 (1R,2S,5S,6R)-3-aza-3-<(tert-butyl)oxycarbonyl>-6-methoxycarbonylbicyclo<3.1.0>hexyl-2-methanol 

Downstream Products

• 326902-26-5 benzyl (1R,2S,5S,6R)-3-aza-3-(tert-butyloxycarbonyl)-6-(methoxycarbonyl)bicyclo[3.1.0]hexane-2-carboxylate 
• 326902-42-5 3-{3-[3-(2,2-dimethyl-propionyl)-6-methoxycarbonyl-3-aza-bicyclo[3.1.0]hexane-2-carbonyl]-6-methoxycarbonyl-3-aza-bicyclo[3.1.0]hexane-2-carbonyl}-3-aza-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid 2-benzyl ester 6-methyl ester 
• 326902-37-8 (1R,2S,5S,6R)-3-[(1R,2S,5S,6R)-3-(2,2-Dimethyl-propionyl)-6-methoxycarbonyl-3-aza-bicyclo[3.1.0]hexane-2-carbonyl]-3-aza-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid 2-benzyl ester 6-methyl ester 
• 326902-32-3 benzyl (1R,2S,5S,6R)-3-aza-3-(2,2-dimethylpropanoyl)-6-(methoxycarbonyl)bicyclo[3.1.0]hexane-2-carboxylate 
• 326902-29-8 (1R,2S,5S,6R)-3-Aza-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid 2-benzyl ester 6-methyl ester 

Relevant academic research and scientific papers

Efficient synthesis of cyclopropane-fused heterocycles with bromoethylsulfonium salt

Lord of the rings! [3.1.0] bicyclic ring systems were synthesized using bromoethylsulfonium triflate and easily available amino acid/aza-Morita-Baylis- Hillman-derived allylic amines. The simple transformation displays a very high degree of diastereoselec

Cyclopropanation reactions of pyroglutamic acid-derived synthons with akylidene transfer reagents

The cyclopropanation of unsaturated lactams 1 and 3 derived from pyroglutamic acid with nucleophilic alkylidene transfer reagents is investigated. Good-to-modest yields of cyclopropanes were obtained with most sulfur ylides explored. Syn/anti selectivity was found to be dependent on the synthon as well as the sulfur ylide. This cyclopropanation methodology is used in the synthesis of arginine and glutamic acid analogues.