220641-23-6

Upstream product

• 76-83-5 trityl chloride 
• 109786-74-5 (R)-3-(4-methoxybenzyloxy)propane-1,2-diol 
• 824-94-2 p-methoxybenzyl chloride 
• 109786-73-4 (S)-4-[(4-methoxybenzyloxy)methyl]-2,2-dimethyl-1,3-dioxolane 

Downstream Products

• 220641-25-8 1-O-(1'-octadecynyl)-2,3-bis-O-(4'-methoxybenzyl)-sn-glycerol 
• 220641-27-0 1-O-(1'-(Z)-octadecenyl)-2,3-bis-O-(4'-methoxybenzyl)-sn-glycerol 
• 220641-24-7 2,3-bis-(4'-methoxybenzyl)-sn-glycerol 
• 352007-14-8 1-O-(1'-octadecynyl)-2-O-methyl-3-O-(4'-methoxybenzyl)-sn-glycerol 
• 352007-13-7 2-O-methyl-3-O-(4'-methoxybenzyl)-sn-glycerol 
• 609848-15-9 C₈₄H₁₀₄O₆ 
• 609848-13-7 C₈₄H₁₀₆O₆ 
• 482621-06-7 C₇₃H₉₈O₇ 
• 482621-12-5 C₇₃H₉₈O₇ 
• 482621-19-2 1-{(R)-3-Dec-9-ynyloxy-2-[20-((S)-2-dec-9-ynyloxy-3-trityloxy-propoxy)-icosa-9,11-diynyloxy]-propoxymethyl}-4-methoxy-benzene 
• 482621-16-9 1-{(R)-3-Dec-9-ynyloxy-2-[20-((R)-2-dec-9-ynyloxy-3-trityloxy-propoxy)-icosa-9,11-diynyloxy]-propoxymethyl}-4-methoxy-benzene 
• 609848-03-5 C₈₀H₉₀O₈ 
• 486403-08-1 C₆₂H₉₂O₈ 
• 486403-27-4 C₆₂H₉₂O₈ 

Relevant academic research and scientific papers

Synthesis of Fluorine-Containing Analogues of 1-Lysoglycerophospholipids via Horner-Wadsworth-Emmons Reaction

An efficient method of synthesizing fluorine-containing analogues of 1-lysoglycerophospholipids (1-LPLs) by introducing a palmitoyl moiety starting from bis(2,2,2-trifluoroethyl)phosphonoacetate (Still-Gennari reagent) is described. The method effectively

Synthesis of bioconjugate sesterterpenoids with phospholipids and polyunsaturated fatty acids

A series of sesterterpenoid bioconjugates with phospholipids and polyunsaturated fatty acids (PUFAs) have been synthesized for biological activity testing as antiproliferative agents in several cancer cell lines. Different substitution analogues of the or

Stereoselective synthesis of the head group of archaeal phospholipid PGP-Me to investigate bacteriorhodopsin-lipid interactions

Phosphatidylglycerophosphate methyl ester (PGP-Me), a major constituent of the archaeal purple membrane, is essential for the proper proton-pump activity of bacteriorhodopsin (bR). We carried out the first synthesis of the bisphosphate head group of PGP-M

PSEUDO-CYCLIC LIPID COMPOUND

PROBLEM TO BE SOLVED: To provide a novel glycerol ester compound or glycerol ether compound that can be synthesized relatively easily, and a molecular aggregate comprising them. SOLUTION: This invention provides a novel pseudo-cyclic lipid compound in which glycerol two molecules bond to univalent and divalent alcohol or carboxylic acid through ether or ester linkage, in which a fluorine atom or a non-terminal triple bond or both of them is introduced in the molecule. COPYRIGHT: (C)2016,JPOandINPIT

Design, synthesis, and self-assembly of an ether and amide linkage-based cyclic lipid

A novel 48-membered cyclic lipid, in which two ether and two amide groups serve as a linker between its hydrophilic and hydrophobic moiety, was synthesized starting from d-1,2-O-isopropylidene-sn-glycerol. The synthetic scheme is featured by the selective

Synthesis and biological evaluation of a novel cardiolipin affinity matrix

Cardiolipin (1) is a dimeric phospholipid found in the mitochondrial membranes of both plants and animals. In order to understand better its role, we report the preparation of an immobilised analogue (2) using phosphoramidite chemistry; the probe has been used successfully to bind a recombinant protein containing a cardiolipin-binding domain.

Synthesis and biological activity of anticancer ether lipids that are specifically released by phospholipase A2 in tumor tissue

The clinical use of anticancer lipids is severely limited by their ability to cause lysis of red blood cells prohibiting intravenous injection. Novel delivery systems are therefore required in order to develop anticancer ether lipids (AELs) into clinicall

Convergent synthesis of antiparallel cyclobolaphiles having two diacetylenes: Mimetics of membrane components that are found in archaea

Chiral 48-membered antiparallel cyclobolaphiles and their diastereomer having two diacetylenes were convergently synthesized utilizing both cross-coupling method (Cul, pyrrolidine) and Glaser intramolecular cyclization, starting from commercially available D- and L-1, 2-O-isopropylidene-sn-glycerol as chiral sources.

Synthesis of plasmalogen via 2,3-Bis-O-(4′-methoxybenzyl)-sn-glycerol

The synthesis of the O-vinyl ether phospholipid plasmalogen 1 from 2,3-bis-O-[p-methoxybenzyl (PMB)]-sn-glycerol (13) is described. Treatment of 13 with potassium hydride, trichloroethylene, and n-butyllithium gave a 1-O-alkynyl glycerol derivative, which