220663-04-7

Upstream product

• 64-19-7 acetic acid 
• 220663-03-6 4-chloro-2-(chloromethyl)-5-phenoxypyridazin-3-(2H)-one 
• 97137-15-0 1-acetoxymethyl-4,5-dichloropyridazin-6-one 
• 108-95-2 phenol 
• 51355-97-6 4,5-dichloro-2-(hydroxymethyl)pyridazin-3(2H)-one 

Downstream Products

• 212622-34-9 5-chloro-4-phenoxypyridazin-6-one 

Relevant academic research and scientific papers

Retro-ene reaction, VI. Functionalization of 4,5-dihalopyridazin-6-ones using 1-acetyloxymethyl-4,5-dihalopyridazin-6-ones as the 1-o, 3-n, 5-o ene- adduct

Functionalization of 1-acetyloxymethyl-4,5-dihalopyridazin-6-ones via retro-ene reaction with some nucleophiles gave regioselectively only 5-halo- 4-substitutedpyridazin-6-ones.

Reaction of 1-chloromethyl-4,5-dichloropyridazin-6-one

Reaction of 1-chloromethyl-4,5-dichloropyridazin-6-one with some nucleophiles such as sodium methoxide, sodium azide, 2-mercaptopyrimidine and phenol gave 2, 3, 4, 7, 8 and 10. 5-Chloro-4-phenoxypyridazin-6-one (10) was also synthesized from 8 through 9.