2207-27-4

Basic information

• Product Name: 1,2,3,4-Tetrachloro-5,5-dimethoxycyclopentadiene
• Synonyms: 1, 2, 3, 4-Tetrachloro-5, 5-dimethoxy-1, 3-cyclopentadiene;1,1-Dimethoxy-2,3,4,5-tetrachlorocyclopentadiene;2,3,4,5-Tetrachloro-1,1-dimethoxycyclopentadiene;2,3,4,5-Tetrachlorocyclopentadienone dimethyl acetal;2,4-Cyclopentadien-1-one, 2,3,4,5-tetrachloro-, dimethyl acetal;5,5-Dimethoxytetrachlorocyclopentadiene;Cyclopentadienone, tetrachloro-, dimethyl acetal;Tetrachlorocyclopentadiene dimethyl ketal
• CAS NO: 2207-27-4
• Molecular Formula: C₇H₆Cl₄O₂
• Molecular Weight: 263.93
• EINECS: 218-623-3
• Product Categories: Halides;Ring Systems;Acetals/Ketals/Ortho Esters;Organic Building Blocks;Oxygen Compounds
• Mol File: 2207-27-4.mol
• Article Data: 6

Chemical Properties

• Melting Point: 26-28 °C
• Boiling Point: 108-110 °C11 mm Hg(lit.)
• Flash Point: 152 °F
• Appearance: /
• Density: 1.501 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0614mmHg at 25°C
• Refractive Index: n20/D 1.525
• Storage Temp.: 2-8°C
• BRN: 477013
• CAS DataBase Reference: 1,2,3,4-Tetrachloro-5,5-dimethoxycyclopentadiene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,3,4-Tetrachloro-5,5-dimethoxycyclopentadiene(2207-27-4)
• EPA Substance Registry System: 1,2,3,4-Tetrachloro-5,5-dimethoxycyclopentadiene(2207-27-4)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• Hazardous Substances Data: 2207-27-4(Hazardous Substances Data)

Usage

Chemical Properties

Yellow liquid

Uses

5,5-Dimethoxy-1,2,3,4-tetrachlorocyclopentadiene, can form endo-adduct with 1,3-cyclopentadiene.

InChI:InChI=1/C7H6Cl4O2/c1-12-7(13-2)5(10)3(8)4(9)6(7)11/h1-2H3

Upstream product

• 77-47-4 hexachlorocyclopentadiene 
• 67-56-1 methanol 
• 124-41-4 sodium methylate 

Downstream Products

• 100961-11-3 6-benzoyl-3,5-dichloro-4-methoxy-pyridine-2-carboxylic acid methyl ester 
• 15725-06-1 1-trimethylstannyl-2,3,4,5-tetrachlorobenzene 
• 1039627-74-1 C₂₂H₂₆Cl₄O₅ 
• 1039627-71-8 C₂₂H₂₆Cl₄O₅ 
• 50874-38-9 1,2,3,4-tetrachloro-9,9-dimethoxy-1,4,4a,8a-tetrahydro-1,4-methanonaphthalene-5,8-dione 
• 140867-29-4 (1R*,4S*,5S*,4'R*)-7,7-dimethoxy-1,2,3,4-tetrachloro-5-<4'-(4'-methyl-2'-phenyl-2'-oxazolinyl)>-bicyclo<2.2.1>hept-2-ene 
• 140867-29-4 (1R*,4S*,5S*,4'S*)-7,7-dimethoxy-1,2,3,4-tetrachloro-5-<4'-(4'-methyl-2'-phenyl-2'-oxazolinyl)>-bicyclo<2.2.1>hept-2-ene 
• 92639-63-9 1,4,5,6-tetrachloro-7,7-dimethoxy-2-(o-bromobenzoyloxymethyl)bicyclo<2.2.1>-5-heptene 
• 82994-60-3 4,5,6-Trichloro-2-(diethoxy-phosphoryl)-isophthalic acid 1-ethyl ester 3-methyl ester 
• 113203-24-0 Benzyl-methyl-((1S,2R,6S,7R)-1,7,8,9-tetrachloro-10,10-dimethoxy-3-oxa-5-aza-tricyclo[5.2.1.0^2,6]deca-4,8-dien-4-yl)-amine 
• 145295-68-7 C₂₇H₂₄Cl₄O₂ 
• 145295-68-7 C₂₇H₂₄Cl₄O₂ 
• 116333-12-1 1,4,5,6-tetrachloro-7,7-dimethoxy-3-dimethylamino-2-phenyl-2-phospha-5-norbornene 
• 135781-87-2 2,3,5-trichloro-4,4-dimethoxy-5-benzyl-2-cyclopenten-1-one 

Relevant articles and documents

Labelled compounds. XV. Hexachlorocyclopentadiene (14C) from hexachloropropene (1,3 14C) and cis 1,2 dichloroethylene

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INHIBITORS OF MTOR-DEPTOR INTERACTIONS AND METHODS OF USE THEREOF

Provided herein are substituted hydrazone compounds useful as inhibitors of DEPTOR. The invention further provides pharmaceutical compositions of the compounds of the invention. The invention also provides medical uses of substituted hydrazone compounds.

Catalytic Enantioselective Desymmetrization of Norbornenoquinones via C(sp2)-H Alkylation

The enantioselective Diels-Alder (DA) reaction with monosubstituted p-benzoquinones is an unmet challenge. A new approach for the enantioselective synthesis of monosubstituted quinone-DA adducts is presented based on C(sp2)-H alkylative desymmetrization of meso-DA adducts. Catalyzed by a tertiary amino-thiourea derivative, this reaction utilizes nitroalkanes as the alkylating agents and generates densely functionalized products bearing at least four contiguous stereogenic centers remote from the reaction site with excellent enantioselectivities.