220714-69-2

Basic information

• Product Name: 2-Pyridinamine,3-fluoro-N-methyl-(9CI)
• Synonyms: 2-Pyridinamine,3-fluoro-N-methyl-(9CI);3-fluoro-N-Methylpyridin-2-aMine
• CAS NO: 220714-69-2
• Molecular Formula: C6H7FN2
• Molecular Weight: 126.1315832
• Product Categories: PYRIDINE;amine| alkyl Fluorine
• Mol File: 220714-69-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 186.4±25.0 °C(Predicted)
• Appearance: /
• Density: 1.186±0.06 g/cm3(Predicted)
• PKA: 4.49±0.10(Predicted)
• CAS DataBase Reference: 2-Pyridinamine,3-fluoro-N-methyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyridinamine,3-fluoro-N-methyl-(9CI)(220714-69-2)
• EPA Substance Registry System: 2-Pyridinamine,3-fluoro-N-methyl-(9CI)(220714-69-2)

Safety Data

• Hazardous Substances Data: 220714-69-2(Hazardous Substances Data)

Upstream product

• 17282-04-1 2-chloro-3-fluoropyridine 
• 74-89-5 methylamine 
• 220714-58-9 pyridinium N-(3'-fluoropyridin-2'-yl)aminide 
• 46224-49-1 (pyridin-1-iumyl)[(pyridin-2-yl)aminide] 

Relevant articles and documents

Iridium-catalyzed enantioselective addition of an: N -methyl C-H bond to α-trifluoromethylstyrenes via C-H activation

The Ir-catalyzed enantioselective addition of an N-methyl C-H bond of 2-(methylamino)pyridine derivatives to α-trifluoromethylstyrenes proceeded via C-H activation to give chiral γ-branched amine derivatives having a trifluoromethyl-substituted stereocenter. It was found that a bulky and electron-withdrawing group at the 3-position of 2-(methylamino)pyridines was necessary for the present C-H addition reaction catalyzed by a cationic iridium/chiral bisphosphine complex.