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15-Hydroxyestrone is a naturally occurring metabolite of the hormone estrogen, specifically derived from the conversion of estrone. It plays a significant role in the endocrine system and has been the subject of research due to its potential impact on health. Some studies suggest that 15-hydroxyestrone may have protective effects against certain diseases, such as breast cancer, due to its antioxidant properties and its ability to inhibit the growth of cancer cells. However, the role of 15-hydroxyestrone in health and disease is complex, and more research is needed to fully understand its effects. It is important to note that the balance of different estrogen metabolites, including 15-hydroxyestrone, can influence an individual's health outcomes, and maintaining a healthy lifestyle and diet can support the body's natural hormonal balance.

2208-13-1

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2208-13-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2208-13-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,2,0 and 8 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 2208-13:
(6*2)+(5*2)+(4*0)+(3*8)+(2*1)+(1*3)=51
51 % 10 = 1
So 2208-13-1 is a valid CAS Registry Number.

2208-13-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 3,15α-dihydroxy-1,3,5(10)-estratrien-17-one

1.2 Other means of identification

Product number -
Other names 15α-hydroxyestrone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2208-13-1 SDS

2208-13-1Relevant academic research and scientific papers

Microbial hydroxylation of 17β-estradiol by Penicillium brevicompactum

Shan, Lihong,Li, Yang,Chen, Yanjie,Yin, Minghui,Huang, Jiajia,Zhang, Zhenzhong,Shi, Xiufang,Liu, Hongmin

, p. 137 - 143 (2016/12/16)

Microbial hydroxylation of 17β-estradiol (1) with Penicillium brevicompactum, a fungal species not used in biotransformation so far, yielded four metabolites: 1, 3, 5-estratriene-3, 15α-diol-17-one (2); 1, 3, 5-estratriene-3, 6α, 17β-triol (3); 1, 3, 5-estratriene-3, 15α, 17β-triol (4); and 1, 3, 5-estratriene-3, 6α, 15α-triol-17-one (5). All the products were determined by 1H NMR, 13C NMR, two-dimensional NMR, and HRMS techniques. Compounds 3, 4, and 5 are reported for the first time via microbial transformation, and 5 is a new compound as far as we know. Possible metabolic pathway of 17β-estradiol via Penicillium brevicompactum was also proposed.

Steroid transformations with Fusarium oxysporum var. cubense and Colletotrichum musae

Wilson, Maureen R.,Gallimore, Winklet A.,Reese, Paul B.

, p. 834 - 843 (2007/10/03)

The utility of two locally isolated fungi, pathogenic to banana, for steroid biotransformation has been studied. The deuteromycetes Fusarium oxysporum var. cubense (IMI 326069, UAMH 9013) and Colletotrichum musae (IMI 374528, UAMH 8929) had not been examined previously for this potential. In general, F. oxysporum var. cubense effected 7α hydroxylation on 3β-hydroxy- Δ5-steroids, 6β, 12β, and 15α hydroxylation on steroidal-4-ene-3-ones, side-chain degradation on 17α,21-dihydroxypregnene-3,20-diones, and 15α hydroxylation on estrone. Both strains were shown to perform redox reactions on alcohols and ketones.

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