220869-82-9Relevant articles and documents
Stereocontrolled synthesis of novel phytosphingosine-type glucosaminocerebrosides
Murakami, Teiichi,Taguchi, Kazuhiro
, p. 989 - 1004 (2007/10/03)
D-ribo-Phytosphingosine 1 was conveniently synthesized from N-benzoyl- D-glucosamine 3 by an improved route in which regioselective O- methanesulfonation and diastereoselective Grignard addition are involved as key steps. Using a synthetic intermediate of 1, novel D-ribo- phytosphingosine-type glycolipids 2a and 2b, unnatural homologues of antifungal cerebrosides Halicylindrosides, were efficiently synthesized in a stereocontrolled manner.