221022-52-2Relevant academic research and scientific papers
An expeditious synthesis of 4-acyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidines (6-acyl uracils) and 4-acyl-6-aryl-2-oxo-2,3-dihydropyrimidines
Khan, M. Wahab,Kundu, Nitya G.
, p. 301 - 318 (2007/10/03)
A facile synthesis of 4-acyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidines (6-acyl uracils) and 4-acyl-6-aryl-2-oxo-2,3-dihydropyrimidines is described where the Friedel-Crafts reaction on 2,6-dichloropyrimidine-4-carbonyl chloride plays a crucial role.
