221038-01-3

Upstream product

• 594-42-3 chlorothio-trichloro-methane 
• 6326-27-8 p-methylbenzamidine hydrochloride 
• 75-70-7 trichloromethyl mercaptan 

Downstream Products

• 1062512-48-4 1-(3-p-tolyl-[1,2,4]thiadiazol-5-yl)-piperazine 
• 1417823-45-0 1-benzo[1,3]dioxol-5-ylmethyl-4-(3-p-tolyl-[1,2,4]thiadiazol-5-yl)-piperazine 
• 1417823-49-4 1-(2-methyl-benzyl)-4-(3-p-tolyl-[1,2,4]thiadiazol-5-yl)-piperazine 

Relevant academic research and scientific papers

1, 2, 4-Thiadiazol-5-Ylpiperazine derivatives useful in the treatment of neurodegenerative diseases

The present invention relates to a compound of formula (IA) The present invention also relates to the use of the compound of formula IA for treating certain neurodegenerative disorders characterized by cytotoxic TAU misfolding and/or aggregation.

1, 2, 4 -THIADIAZOL- 5 -YLPIPERAZINE DERIVATIVES USEFUL IN THE TREATMENT NEURODEGENERATIVE DISEASES

The present invention relates to a compound of formula (IA) The present invention also relates to the use of the compound of formula IA for treating certain neurodegenerative disorders characterized by cytotoxic TAU misfolding and/or aggregation.

Diaryl substituted thiazoles useful in the treatment of fungal infections

Disclosed is a novel class of thiazole, thiadiazole, and oxadiazole compounds which are substituted at their nuclear carbons by aromatic moieties. These compounds exhibit antifungal activity against a variety of fungi including strains which have proven to be resistant to treatment with known antifungal agents such as Fluconazole.