221040-36-4 Usage
Molecular structure
A complex ester derived from pyrrolidinedicarboxylic acid and thiazinylmethyl carboxylic acid, with additional methyl and isopropyl groups attached.
Classification
A derivative of proline, a common amino acid found in proteins.
Pharmaceutical and biological applications
The compound has potential uses in the pharmaceutical and biological fields due to its unique structure and properties.
Stereochemistry
The compound has a specific (2R)configuration, which is important for its activity and interactions in biological systems.
Ester formation
The compound is an ester, formed by the reaction between the carboxylic acid group of pyrrolidinedicarboxylic acid and the hydroxyl group of thiazinylmethyl carboxylic acid.
Chirality
The presence of chiral centers in the molecule, specifically the (2R)configuration, contributes to its unique properties and potential applications.
Isopropyl group
The presence of an isopropyl group (1,1-dimethylethyl) in the molecule adds steric hindrance and may influence the compound's interactions with other molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 221040-36-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,1,0,4 and 0 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 221040-36:
(8*2)+(7*2)+(6*1)+(5*0)+(4*4)+(3*0)+(2*3)+(1*6)=64
64 % 10 = 4
So 221040-36-4 is a valid CAS Registry Number.
221040-36-4Relevant academic research and scientific papers
Design, synthesis, and in vitro activity of peptidomimetic inhibitors of myeloid differentiation factor 88
Fantò, Nicola,Gallo, Grazia,Ciacci, Andrea,Semproni, Mauro,Vignola, Davide,Quaglia, Marco,Bombardi, Valentina,Mastroianni, Domenico,Zibella, M. Pia,Basile, Giancarlo,Sassano, Marica,Ruggiero, Vito,De Santis, Rita,Carminati, Paolo
, p. 1189 - 1202 (2008/09/20)
We describe the design and synthesis of a peptidomimetic library derived from the heptapeptide AC-RDVLPGT-NH2, belonging to the Toll/IL-1 receptor (TIR) domain of the adaptor protein MyD88 and effective in inhibiting its homodimerization. The a
Design, synthesis, and dopamine receptor modulating activity of spiro bicyclic peptidomimetics of L-prolyl-L-leucyl-glycinamide
Khalil, Ehab M.,Ojala, William H.,Pradhan, Ashish,Nair, Venugopalan D.,Gleason, William B.,Mishra, Ram K.,Johnson, Rodney L.
, p. 628 - 637 (2007/10/03)
In the present study, the synthesis of the 5.5.6. and 5.6.5. spiro bicyclic lactam PLG peptidomimetics, compounds 3 and 4, respectively, was undertaken. These peptidomimetics were designed to examine the following: (1) the effect that changing the size of
