221044-90-2

Upstream product

• 541-41-3 chloroformic acid ethyl ester 
• 221044-89-9 1-phenyl-1,2-dideoxy-4,5:6,8-di-O-isopropylidene-D-talo-D-glycero-oct-1-yne 
• 4440-01-1 lithium phenylacetylide 
• 536-74-3 phenylacetylene 
• 357604-61-6 2,3:4,6-di-O-isopropylidene-D-mannopyranose 

Downstream Products

• 221044-91-3 Carbonic acid (R)-1-[(4R,5R)-5-((4R,5R)-2,2-dimethyl-5-phenoxythiocarbonyloxy-[1,3]dioxan-4-yl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-3-phenyl-prop-2-ynyl ester ethyl ester 

Relevant academic research and scientific papers

A novel entry to 5a-carba-hexopyranoses from carbohydrates based on a 6-exo-dig radical cyclization: Synthesis of 5a-carba-β-D-mannopyranose pentaacetate

Carbohydrate-derived 2,3:4,6-diacetonides which are homologated at C-1 by reaction with phenyl acetylide undergo a 6-exo-dig radical cyclization, from a radical located at C-5, to yield highly functionalized cyclohexanes that are correlated with carba-sugars.

Stereodivergent synthesis of 5a-carba-hexopyranoses from carbohydrates via 6-exo-dig radical cyclization: Preparation of 5a-carba-β-D-manno-, α-D-allo-, β-L-talo- and α-L-gulopyranose pentaacetates from D-mannose

Four carbasugars, 5a-carba-β-D-manno-, α-D-allo-, β-L-talo- and α-L-gulopyranose pentaacetates, have been prepared in a stereodivergent manner from D-mannose. Alkynyl derivatives of 2,3:4,6-di-O-isopropylidene-D-mannopyranose, which are prepared by homolo