221056-41-3Relevant academic research and scientific papers
Studies on the chemistry of 2-(2-oxo-3-phenylpropyl)-benzaldehydes: Novel total synthesis of 3-phenylnaphthalen-2-ols and 2-hydroxy-3-phenyl-1,4- naphthoquinones
Martínez, Ana,Fernández, Marcos,Estévez, Juan C.,Estévez, Ramón J.,Castedo, Luis
, p. 485 - 492 (2007/10/03)
We describe the first studies on the chemistry of 2-(2-oxo-3-phenylpropyl) benzaldehydes, which were converted into 3-benzylisochromen-1-ones via the corresponding 2-(2-oxo-3-phenylpropyl)benzoic acid. The 2-(2-oxo-3-phenylpropyl) benzaldehydes proved to be convenient starting materials for the synthesis of 3-phenyl-2-naphthols. Oxidation of the latter compounds resulted in a novel, efficient synthesis of 3-phenyl-1,2-naphthoquinones, which were efficiently transformed into 2-hydroxy-3-phenyl-1,4-naphthoquinones.
A convenient synthesis of (dl)-3-benzyl-3,4-dihydroisocoumarin as a model of Feralolide
Rama, Nasim H.,Iqbal, Rashid,Zamani, Khosrow,Malik, Abdul
, p. 1021 - 1023 (2007/10/03)
(dl)-3-Benzyl-3,4-dihydroisocoumarin 6, a model of Feralolide, has been synthesized through 3-benzylisocoumarin 2 which is prepared by the condensation of phenylacetyl chloride with homophthalic acid. Alkaline hydrolysis of 2 yielded the keto-acid 3 which
