2211-65-6Relevant academic research and scientific papers
I2/TBHP mediated diastereoselective synthesis of spiroaziridines
Ashitha, Kizhakkan Thiruthi,Vinaya, Puthiya Purayil,Krishna, Ajay,Vincent, Deepthy Cheeran,Jalaja, Renjitha,Varughese, Sunil,Somappa, Sasidhar Balappa
supporting information, p. 1588 - 1593 (2020/03/06)
Eventhough spiroheterocycles are considered as emerging drug candidates, synthesis of spiroaziridines has not been well explored so far. Herein, we disclose an efficient I2/TBHP mediated diastereoselective synthesis of N-alkyl spiroaziridines from primary amines and easily accessible α,β-unsaturated ketones. The reaction is also compatible for the synthesis of 2-aroylaziridines.
A Rapid Synthesis of Aziridine Derivatives over Bentonite in 'Dry Media'
Saoudi, Aicha,Hamelin, Jack,Benhaoua, Hadj
, p. 492 - 493 (2007/10/03)
Functionalized aziridines are synthesized from dibromo compounds and primary aliphatic amines in the absence of solvent over bentonite as a solid support; in some examples microwave activation is compared to normal heating.
