2211-95-2

Usage

Uses

Used in Adhesives Industry:
Oxirane, [(3-chlorophenoxy)methyl]is used as a key component in the production of epoxy resins for adhesives, due to their strong bonding properties and resistance to heat and chemicals, making them suitable for a wide range of applications.
Used in Coatings Industry:
In the coatings industry, Oxirane, [(3-chlorophenoxy)methyl]is utilized as a constituent of epoxy resins, which provide coatings with excellent adhesion, durability, and resistance to various environmental factors.
Used in Composites Industry:
Oxirane, [(3-chlorophenoxy)methyl]is employed in the manufacturing of composite materials, where epoxy resins offer high strength, lightweight, and corrosion resistance, making them ideal for applications in aerospace, automotive, and construction sectors.
Used as a Solvent:
Oxirane, [(3-chlorophenoxy)methyl]also serves as a solvent in certain industrial processes, taking advantage of its ability to dissolve a variety of substances.
Used as a Chemical Intermediate:
Furthermore, Oxirane, [(3-chlorophenoxy)methyl]is used as a chemical intermediate in the synthesis of other chemicals, highlighting its importance in the chemical industry.
However, it is crucial to handle Oxirane, [(3-chlorophenoxy)methyl]with care, as it is a potential carcinogen and can cause irritation to the skin, eyes, and respiratory system if not properly managed.

Upstream product

• 108-43-0 3-monochlorophenol 
• 106-89-8 epichlorohydrin 
• 24824-86-0 1-(allyloxy)-3-chlorobenzene 

Downstream Products

• 175718-36-2 1-azido-3-(3-chlorophenoxy)-2-propanol 
• 129098-53-9 (S)-2-(3-chlorophenoxymethyl)oxirane 
• 129098-54-0 (S)-2-(3-chloro-phenoxymethyl)-oxirane 
• 46457-69-6 2-[3-chlorophenoxymethyl]-morpholine 
• 83195-08-8 3-[3-(3-Chloro-phenoxy)-2-hydroxy-propylamino]-propionic acid ethyl ester; hydrochloride 
• 4427-92-3 (4S)-4-phenyl[1,3]dioxolan-2-one 
• 90971-11-2 (R)-1-phenyl-1,2-ethanediol carbonate 

Relevant academic research and scientific papers

Substituted diaryl compound and preparation method and application thereof

The invention relates to the field of medicinal chemistry, in particular to a substituted diaryl compound (I). The preparation method comprises the following steps: medicine preparation and medical application thereof. Test results show that the substituted diaryl compound has a good inhibition effect on human lung cancer (A549), human ovarian cancer (SKOV3), human melanoma (A375) and human colon cancer (LOVO) cells. Formula (I):

Chemoselective Epoxidation of Allyloxybenzene by Hydrogen Peroxide Over MFI-Type Titanosilicate

The chemoselective synthesis of 2-(phenoxymethyl)oxirane from allyloxybenzene is achieved with over 90 % yield in a sustainable reaction system using titanium-substituted silicalite-1 (TS-1) as a catalyst, hydrogen peroxide (H2O2) as an oxidant, and a mixture of MeOH/MeCN as a solvent at 40 °C. No acid-catalyzed side reactions prompted by the Lewis acidity of the Ti active site in TS-1 are observed. The TS-1 catalyst can also promote the formation of oxiranes from various p-substituted allyloxybenzenes in good yields. The reaction mechanism is investigated through the reaction with other allyloxy compounds. The results, which are supported by DFT calculations, indicate that an active species of Ti peroxides formed from the reaction of TS-1 with H2O2 selectively oxidizes the allyloxybenzene to 2-(phenoxymethyl)oxirane.

Structure-guided design, synthesis and evaluation of oxazolidinone-based inhibitors of norovirus 3CL protease

Acute nonbacterial gastroenteritis caused by noroviruses constitutes a global public health concern and a significant economic burden. There are currently no small molecule therapeutics or vaccines for the treatment of norovirus infections. A structure-gu

Synthesis and bovine β3-adrenergic agonistic activities of a novel series of aryloxypropanolamines

We synthesized a novel series of 21 aryloxypropanolamine compounds characterized by N-alkyl, aralkyl, and aryl substituents. The compounds showed potent β3-adrenergic agonistic activities in Chinese hamster ovary cells expressing the bovine β3-adrenoceptors with Kact and Ki values of 4.2 ± 3.0 nM and 459 ± 169 nM respectively, for the ligand with the best compromise between potency and affinity. Structure-activity relationships are discussed.

Aryloxypropanolaminotetralins, a process for their preparation and pharmaceutical compositions containing them

Aryloxypropanolaminotetralins with beta-antagonist activity of the formula STR1 wherein R is hydrogen, hydroxy or methoxy and Ar is an optionally substituted aromatic or heteroaromatic group, in optically active or inactive form as well as their acid addition salts are described.A process for their preparation and pharmaceutical compositions containing the compounds of formula (i) or their pharmaceutically acceptable acid addition salts, are also described.