22112-83-0

Basic information

• Product Name: MESO-TETRA(4-CARBOXYPHENYL)PORPHINE TETRAMETHYL ESTER
• Synonyms: MESO-TETRA(4-CARBOXYPHENYL)PORPHINE TETRAMETHYL ESTER;5,10,15,20-TETRAKIS-(4-METHOXYCARBONYLPHENYL)-21,23H-PORPHYRIN;RARECHEM AS SA 0036;TETRAMETHYL MESO-TETRAPHENYLPORPHINE-4,4',4'',4'''-TETRACARBOXYLATE;5,10,15,20-Tetra(4-carboxyphenyl)porphine tetramethyl ester;5,10,15,20-meso-Tetrakis[4-(methoxycarbonyl)phenyl]porphyrin;Tetramethyl 4,4',4'',4'''-(5,10,15,20-porphyrintetrayl)tetrabenzo ate
• CAS NO: 22112-83-0
• Molecular Formula: C₅₂H₃₈N₄O₈
• Molecular Weight: 846.88
• Product Categories: Porphyrins
• Mol File: 22112-83-0.mol

Chemical Properties

• Melting Point: 250 °C
• Appearance: /
• Density: 1.319±0.06 g/cm3(Predicted)
• CAS DataBase Reference: MESO-TETRA(4-CARBOXYPHENYL)PORPHINE TETRAMETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: MESO-TETRA(4-CARBOXYPHENYL)PORPHINE TETRAMETHYL ESTER(22112-83-0)
• EPA Substance Registry System: MESO-TETRA(4-CARBOXYPHENYL)PORPHINE TETRAMETHYL ESTER(22112-83-0)

Safety Data

• Hazardous Substances Data: 22112-83-0(Hazardous Substances Data)

Usage

Uses

Used in Fluorescence Imaging:
MESO-TETRA(4-CARBOXYPHENYL)PORPHINE TETRAMETHYL ESTER is used as a fluorescent probe in fluorescence imaging due to its strong and stable fluorescence emission. Its ability to bind with metal ions and penetrate biological membranes enhances its potential for imaging applications in biological systems.
Used in Photodynamic Therapy:
In the medical field, MESO-TETRA(4-CARBOXYPHENYL)PORPHINE TETRAMETHYL ESTER is used as a photosensitizer in photodynamic therapy for cancer treatment. Its strong absorption in the visible light region and efficient generation of reactive oxygen species upon light irradiation make it effective in inducing cell death in cancerous tissues.
Used in Catalysis:
MESO-TETRA(4-CARBOXYPHENYL)PORPHINE TETRAMETHYL ESTER is utilized as a catalyst in various chemical reactions, particularly in oxidation and reduction processes. Its ability to form complexes with metal ions and its robust structure contribute to its catalytic activity and stability.
Used in Pharmaceutical Industry:
MESO-TETRA(4-CARBOXYPHENYL)PORPHINE TETRAMETHYL ESTER is used as a precursor in the synthesis of pharmaceutical compounds. Its unique structure and functional groups can be modified to create new drug candidates with potential therapeutic applications.
Used in Material Science:
In the field of material science, MESO-TETRA(4-CARBOXYPHENYL)PORPHINE TETRAMETHYL ESTER is used in the development of functional materials, such as organic semiconductors and light-harvesting systems. Its photophysical properties and ability to form complexes with metal ions make it a valuable component in designing advanced materials with specific electronic and optical properties.

Upstream product

• 109-97-7 pyrrole 
• 1571-08-0 methyl 4-formylbenzoate 
• 13750-81-7 N-methyl-2-imidazolcarboxaldehyde 
• 167482-99-7 5-(4-carbomethoxyphenyl)dipyrromethane 
• 3609-53-8 methyl 4-acetylbenzoate 
• 14609-54-2 tetrakis(4-carboxyphenyl)porphyrin 
• 67-56-1 methanol 
• 121-33-5 vanillin 
• 500-22-1 3-pyridinecarboxaldehyde 
• 872-85-5 pyridine-4-carbaldehyde 
• 153364-63-7 4-(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)benzaldehyde 
• 802294-64-0 propionic acid 
• 171824-87-6 2,5-[α-hydroxy-α-(p-tolyl)]methylfuran 
• 1312997-06-0 methyl 4-[hydroxyl(5-{hydroxyl[4-(methoxycarbonyl)phenyl]methyl}furan-2-yl)methyl]benzoate 

Downstream Products

• 64413-48-5 [5,10,15,20-tetrakis(4-methoxycarbonylphenyl)porphyrinato]Fe(III) chloride 
• 19496-19-6 [5,10,15,20-tetrakis(4-methoxycarbonylphenyl)porphyrinato]-Co(II) 
• 853568-53-3 tetra methyl 4,4′,4″,4′″-(copperporphyrin-5,10,15,20-tetrayl)tetrabenzoate 
• 19496-19-6 [5,10,15,20-tetrakis(4-methoxycarbonylphenyl)porphyrinato]cobalt(II) 
• 144810-99-1 {meso-5,10,15,20-tetrakis{4-(methoxycarbonyl)phenyl}porphyrinato}tin(IV) dichloride 
• 58188-48-0 [5,10,15,20-tetrakis(4-methoxycarbonylphenyl)porphyrinato]-nickel(II) 
• 64413-48-5 4,4′,4″,4?-(iron(III)porphine-5,10,15,20-tetrayl)-tetrakis(methyl benzoate) chloride 
• 64466-25-7 [[μ-5,10,15,20-tetrakis(4-methoxycarbonylphenyl)porphyrinato(2-)]zinc(II)] 

Relevant articles and documents

Efficient routes to A3B-type meso -(4-Carboxyphenyl) porphyrin derivatives

A3B-type meso-(4-carboxyphenyl) porphyrins were prepared either by stepwise coupling of aniline substituents to meso-tetrakis(4-carboxyphenyl) porphyrin (TCPP) or by utilizing its partially protected trimethyl ester derivative. We demonstrate t

Coupling of a new porphyrin photosensitizer and cobaloxime cocatalyst for highly efficient photocatalytic H2evolution

Photocatalytic hydrogen evolution (PHE) is a promising strategy to produce environmentally friendly clean energy with the use of solar power and water. For this, developing an efficient and noble metal free photocatalytic system (PS) comprising high light

H2S-Activable MOF Nanoparticle Photosensitizer for Effective Photodynamic Therapy against Cancer with Controllable Singlet-Oxygen Release

Photodynamic therapy (PDT) has emerged as an important minimally invasive tumor treatment technology. The search for an effective photosensitizer to realize selective cancer treatment has become one of the major foci in recent developments of PDT technolo

Ultrasonic assisted fabrication of dual function surface on PET and preparation of single component ink to attain efficient self-cleaning function via digital printing

The self-cleaning effects of polyethylene terephthalate fabric (PET) through the photocatalytic effects of TiO2 (T), porphyrin (P) and silane (S) have been explored ultrasonically using bath type (WUC-D22H, Daihan Scientific, Korea). The ultras

Towards synthetic-porphyrin/monoclonal antibody conjugates

The synthesis of an unsymmetrically meso-aminoalkoxyphenyl-substituted porphyrin, and its conjugation to a monoclonal antibody (mAb), are described.

Two novel tcpp porphyrinic compounds: In situ syntheses, characterization and reaction mechanism

Two novel porphyrinic compounds, {Zn[TCPP(CH2CH3)2(CH3)2]}n (1) and TCPP(CH3)4 (2) (TCPP = meso-Tetra(4-carboxyphenyl)porphyrin), with the TCPP(CH2CH3

Triplet–Triplet Annihilation Upconversion in a MOF with Acceptor-Filled Channels

Photon upconversion has enjoyed increased interest in the last years due to its high potential for solar-energy harvesting and bioimaging. A challenge for triplet–triplet annihilation upconversion (TTA-UC) processes is to realize these features in solid materials without undesired phase segregation and detrimental dye aggregation. To achieve this, we combine a palladium porphyrin sensitizer and a 9,10-diphenylanthracene annihilator within a crystalline mesoporous metal–organic framework using an inverted design. In this modular TTA system, the framework walls constitute the fixed sensitizer, while caprylic acid coats the channels providing a solventlike environment for the mobile annihilator in the channels. The resulting solid material shows green-to-blue delayed upconverted emission with a luminescence lifetime of 373±5 μs, a threshold value of 329 mW cm?2 and a triplet–triplet energy transfer efficiency of 82 %. The versatile design allows straightforward changing of the acceptor amount and type.

Zirconium-metalloporphyrin PCN-222: Mesoporous metal-organic frameworks with ultrahigh stability as biomimetic catalysts

Biomimetic MOF: Extremely stable MOFs with different open metal sites and ultra-large 1D channels, PCN-222 (Fe, Mn, Co, Ni, Cu, and Zn), have been assembled with eight-connected Zr6 clusters and redox-active metalloporphyrin motifs. PCN-222(Fe) shows peroxidase-like activity in aqueous solution, exhibiting highly effective biomimetic oxidation on a number of substrates. Copyright

Chlorin-Based Nanoscale Metal-Organic Framework Systemically Rejects Colorectal Cancers via Synergistic Photodynamic Therapy and Checkpoint Blockade Immunotherapy

Photodynamic therapy (PDT) can destroy local tumors and minimize normal tissue damage, but is ineffective at eliminating metastases. Checkpoint blockade immunotherapy has enjoyed recent success in the clinic, but only elicits limited rates of systemic ant

Spectroscopy of protonated tetraphenylporphyrins with amino/carbomethoxy substituents: Hyperporphyrin effects and evidence for a monoprotonated porphyrin

Spectrophotometric titrations for a full series of para-amino/carbomethoxy- substituted tetraphenylporphyrins were carried out using methanesulfonic acid in DMSO to study the hyperporphyrin effect across different substitution patterns. The series included zero, one, two (cis and trans), three, and four amino groups, with the remaining para substituents carbomethoxy groups. With increasing numbers of aminophenyl groups, the relative basicity increased and the hyperporphyrin effect increased, marked by a strong red band and a split Soret band. The cis diamino derivative showed a stronger hyperporphyrin effect compared to the trans isomer, which can be explained based on simple resonance forms. For the monoamino derivative, an initial increase in the Soret band upon acid titration along with well-defined isosbestic points provided evidence for a monoprotonated porphyrin, distinct from the diprotonated and triprotonated states. The relative stability of this unusual intermediate is proposed to be due to charge delocalization of the first cation to the single amino group and destabilization of the second protonation by the electron-withdrawing carbomethoxy substituents.